Document Detail


Direct analysis of illicit drugs by desorption atmospheric pressure photoionization.
MedLine Citation:
PMID:  18320545     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The feasibility of desorption atmospheric pressure photoionization (DAPPI) in the direct analysis of illicit drugs was demonstrated by the analysis of confiscated drug samples of various forms such as tablets, blotter paper, and plant resin and bloom. 3,4-Methylenedioxymethamphetamine (MDMA), amphetamine, phenazepam, and buprenorphine were detected from the analyzed tablets, lysergic acid diethylamide (LSD) and bromobenzodifuranylisopropylamine (bromo-Dragonfly, ABDF) from blotter paper, and Delta(9)-tetrahydrocannabinol (THC) and cannabinol from Cannabis Sativa bloom and resin. The amphetamines, phenazepam and ABDF showed protonated molecules independent of the solvent used, whereas buprenorphine, LSD and the cannabinoids showed molecular ions with toluene and protonated molecules with acetone as the solvent.
Authors:
Tiina J Kauppila; Ville Arvola; Markus Haapala; Jaroslav Pól; Laura Aalberg; Ville Saarela; Sami Franssila; Tapio Kotiaho; Risto Kostiainen
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Rapid communications in mass spectrometry : RCM     Volume:  22     ISSN:  0951-4198     ISO Abbreviation:  Rapid Commun. Mass Spectrom.     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-17     Completed Date:  2008-05-29     Revised Date:  2009-05-20    
Medline Journal Info:
Nlm Unique ID:  8802365     Medline TA:  Rapid Commun Mass Spectrom     Country:  England    
Other Details:
Languages:  eng     Pagination:  979-85     Citation Subset:  IM    
Copyright Information:
(c) 2008 John Wiley & Sons, Ltd.
Affiliation:
Division of Pharmaceutical Chemistry, Faculty of Pharmacy, P.O. Box 56, FI-00014 University of Helsinki, Finland. tiina.kauppila@helsinki.fi
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MeSH Terms
Descriptor/Qualifier:
Adsorption
Atmospheric Pressure
Bromobenzoates / analysis*,  chemistry
Feasibility Studies
Photochemistry / methods*
Propylamines / analysis*,  chemistry
Reproducibility of Results
Sensitivity and Specificity
Spectrometry, Mass, Electrospray Ionization
Street Drugs / analysis*,  chemistry*
Substance Abuse Detection / methods*
Chemical
Reg. No./Substance:
0/1-(8-bromobenzo(1,2-b;4,5-b')difuran-4-yl)-2-aminopropane; 0/Bromobenzoates; 0/Propylamines; 0/Street Drugs

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