Document Detail


Direct Synthesis of Pentafluoroethyl Copper from Pentafluoropropionate as an Economical C2F5 Source: Application to Pentafluoroethylation of Arylboronic Acids and Aryl Bromides.
MedLine Citation:
PMID:  24926803     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The direct synthesis of pentafluoroethyl copper (CuC2F5) from a cuprate reagent and ethyl pentafluoropropionate as one of the most economical and useful pentafluoroethyl sources was accomplished. The advantages of this method are; all the reagents employed are low-cost and operationally simple, and the CuC2F5 reagent is prepared in virtually quantitative yield. Furthermore, the CuC2F5 reagent prepared was successfully applied to two types of pentafluoroethylations with arylboronic acids and aryl bromides to provide the pentafluoroethylated aromatic products in good-to-excellent yields, including large scale operations.
Authors:
Hiroki Serizawa; Kohsuke Aikawa; Koichi Mikami
Related Documents :
22048233 - Combining different analytical approaches to identify odor formation mechanisms in poly...
20727773 - Identification of novel antitubercular compounds through hybrid virtual screening appro...
24937203 - Rhodium(iii)-catalyzed regioselective c2-amidation of indoles with n-(2,4,6-trichlorobe...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-6-13
Journal Detail:
Title:  Organic letters     Volume:  -     ISSN:  1523-7052     ISO Abbreviation:  Org. Lett.     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-6-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890393     Medline TA:  Org Lett     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Transient Receptor Potential Channels as Targets for Phytochemicals.
Next Document:  Near-infrared Light Responsive Synthetic c-di-GMP Module for Optogenetic Applications.