| Direct One-Pot Synthesis of Primary 4-Amino-2,3-diaryl-quinolines via Suzuki-Miyaura Cross-Coupling of 2-Aryl-4-azido-3-iodoquinolines with Arylboronic Acids. | |
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MedLine Citation:
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PMID: 22027952 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Palladium-catalyzed Suzuki-Miyaura cross-coupling of 2-aryl-4-azido-3-iodo-quinolines with arylboronic acids afforded the corresponding primary 4-amino-2,3-diarylquinolines in a single-pot operation along with symmetrical biaryls and traces of the 2,3-diaryl-4-azidoquinolines. A plausible mechanism, which implicates palladium hydride species in the reduction of the incipient 2,3-diaryl-4-azidoquinolines to afford the 4-amino-2,3-diarylquinolines is proposed. |
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Authors:
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Malose Jack Mphahlele; Mamasegare Mabel Mphahlele |
Publication Detail:
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Type: Journal Article Date: 2011-10-25 |
Journal Detail:
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Title: Molecules (Basel, Switzerland) Volume: 16 ISSN: 1420-3049 ISO Abbreviation: Molecules Publication Date: 2011 |
Date Detail:
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Created Date: 2011-10-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100964009 Medline TA: Molecules Country: Switzerland |
Other Details:
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Languages: eng Pagination: 8958-72 Citation Subset: IM |
Affiliation:
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Department of Chemistry, College of Science, Engineering and Technology, University of South Africa, P.O. Box 392, Pretoria 0003, South Africa. mphahmj@unisa.ac.za. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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