| Direct MRI detection of the neuronal magnetic field: the effect of the dendrite branch. | |
| | |
MedLine Citation:
|
PMID: 20808026 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
In recent years, neuronal current MRI (nc-MRI) was proposed as a new imaging method to directly map the magnetic field change caused by neuronal activity. Nc-MRI could offer improved spatial and temporal resolution compared to blood hemodynamics-based functional magnetic resonance imaging (fMRI). In this paper, with a finite current dipole as the model of dendrite or dendrite branch, we investigated the spatial distribution of the magnetic field generated by synchronously activated neurons to evaluate the possibility of nc-MRI. Our simulations imply that the existence of a dendrite branch may not only increase the strength of the neuronal magnetic field (NMF), but also raise the non-uniform and unsymmetry of the NMF; therefore, it can enhance the detectability of the neuronal current magnetic field by MRI directly. The results show that the signal phase shift is enlarged, but it is unstable and is still very small, <<1 radian, while the magnitude signal may be strong enough for a typical MRI voxel to be detected. We suggest making further efforts to measure the magnitude signal which may induce a large effect in an nc-MRI experiment. |
| | |
Authors:
|
Ying-Ling Huang; Hong-Chuan Xiong; De-Zhong Yao |
Related Documents
:
|
7998546 - Sonography by the radiologist: self-referral, turf battles, and marketing. 4089196 - Magnetic fields as environmental specific cues for morphine-induced analgesia: interact... 12148746 - X-ray micro-ct with a displaced detector array. 8274986 - Experience with a multichannel system for biomagnetic study. 2338896 - Volumetric measurement of canine gliomas using mri. 18083656 - Treatment of equine cheek teeth by mechanical widening of diastemata in 60 horses (2000... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-08-31 |
Journal Detail:
|
Title: Physics in medicine and biology Volume: 55 ISSN: 1361-6560 ISO Abbreviation: Phys Med Biol Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-09-02 Completed Date: 2010-12-15 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0401220 Medline TA: Phys Med Biol Country: England |
Other Details:
|
Languages: eng Pagination: 5599-616 Citation Subset: IM |
Affiliation:
|
Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, People's Republic of China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Dendrites / metabolism* Humans Magnetic Resonance Imaging / methods* Magnetics* Models, Biological* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Intrathoracic fracture-dislocation of the humeral head: a case report.
Next Document: Dosimetric properties of Gafchromic(R) EBT films in medical carbon ion beams.