| Direct Catalytic Asymmetric Addition of Allylic Cyanides to Aldehydes for Expeditious Access to Enantioenriched Unsaturated δ-Valerolactones. | |
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MedLine Citation:
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PMID: 23208841 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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A direct catalytic asymmetric γ-addition of allyl cyanide to aldehydes promoted by soft Lewis acid/hard Brønsted base cooperative catalysis is described. The resulting homoallylic alcohols bearing a Z-configured α,β-unsaturated nitrile allow rapid access to enantioenriched δ-valerolactones. |
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Authors:
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Yasunari Otsuka; Hisashi Takada; Shigeo Yasuda; Naoya Kumagai; Masakatsu Shibasaki |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-12-3 |
Journal Detail:
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Title: Chemistry, an Asian journal Volume: - ISSN: 1861-471X ISO Abbreviation: Chem Asian J Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2012-12-4 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101294643 Medline TA: Chem Asian J Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
Affiliation:
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Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021 (Japan), Fax: (+81) 3-3441-7589 http://www.bikaken.or.jp/research/group/shibasaki/shibasaki-lab/index_e.html. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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