Document Detail


Direct Amide Coupling of Non-activated Carboxylic Acids and Amines Catalysed by Zirconium(IV) Chloride.
MedLine Citation:
PMID:  22368037     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Amidst the green: A green, mild and effective protocol for the direct formation of secondary and tertiary amides from non-activated carboxylic acids and amines in good to excellent yields by employing ZrCl(4) as the catalyst is presented. The amide coupling protocol proved to be suitable for scaled up syntheses, and the mild reaction conditions conserve the enantiopurity of chiral starting materials.
Authors:
Helena Lundberg; Fredrik Tinnis; Hans Adolfsson
Related Documents :
6083777 - Histochemical characterization of the naso-labial glands of two species of ruminants (o...
1690867 - Astrocytes and the plaques of alzheimer's disease.
20221937 - Synthesis and cyclisation of 1,4-disubstituted semicarbazides.
22654897 - Fatty acid accumulation and resulting pparα activation in fibroblasts due to trifuncti...
20669817 - Evidence for the efficacy of an 8% strontium acetate dentifrice for instant and lasting...
738937 - Cystinuria in a maned wolf.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-24
Journal Detail:
Title:  Chemistry (Weinheim an der Bergstrasse, Germany)     Volume:  -     ISSN:  1521-3765     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-2-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9513783     Medline TA:  Chemistry     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Affiliation:
Department of Organic Chemistry, Stockholm University, The Arrhenius Laboratory, SE-106 91, Stockholm (Sweden), Fax: (+46) 8-154908.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memor...
Next Document:  The Cortisol Response to Hypobaric Hypoxia at Rest and Post-Exercise.