| Dipyridamole-echocardiography test as a clue for assessing the organic 'ceiling' of individual coronary reserve. | |
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MedLine Citation:
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PMID: 3816837 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Twenty-four patients with a history of effort angina, a positive exercise stress test (EST) and coronary artery disease were enrolled in the study; 12 patients had a positive dipyridamole-echocardiography test (DET) and 12 had a negative DET. Each patient performed a total of 4 ESTs in the absence of therapy on two successive days; for each test the rate-pressure product (RPP), an established index of myocardial oxygen demand, was measured at the onset of ischaemia (ST depression greater than 0.15 mV) or at the peak of maximal exercise (if a repeated EST was negative). Taking into account the lowest of the 4 RPP values (X 1/100) in each patient, there was no significant difference between DET-negatives and DET-positives (185.2 +/- 49.3 vs 157.4 +/- 32.4). Conversely, when considering the highest of the 4 RPP values in each patient, there was a significant difference between DET-negatives and DET-positives (280.3 +/- 63.9 vs 183.3 +/- 37.0; p less than 0.01). Thus, DET may provide a clinically useful tool for assessing in the individual the organic 'ceiling' of coronary reserve, by eliminating the variability in coronary tone, which may affect EST reproducibility and the correct evaluation of the impairment of organic coronary reserve. |
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Authors:
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E Picano; P Marraccini; F Lattanzi; D Levantesi; M Masini; M Dalle Vacche; A Distante; A L'Abbate |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European heart journal Volume: 8 ISSN: 0195-668X ISO Abbreviation: Eur. Heart J. Publication Date: 1987 Jan |
Date Detail:
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Created Date: 1987-04-13 Completed Date: 1987-04-13 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8006263 Medline TA: Eur Heart J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 38-44 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Angina Pectoris / physiopathology* Angina, Unstable / diagnosis, etiology, physiopathology* Blood Pressure Coronary Angiography Coronary Disease / complications, diagnosis, physiopathology* Dipyridamole / diagnostic use* Echocardiography Exercise Test Female Heart Rate Humans Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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58-32-2/Dipyridamole |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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