Document Detail


Dipeptides in parenteral nutrition: from basic science to clinical applications.
MedLine Citation:
PMID:  8289765     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The use of intravenous dipeptides shows great promise as an avenue for the provision of amino acids that may otherwise be difficult to deliver via nutrient infusions. The physical/chemical properties and metabolism of numerous dipeptides have now been explored in experimental and human studies. It has been found that these agents have the capacity to spare nitrogen and support serum protein levels in a fashion equivalent to that of intravenous free amino acids. An additional benefit is the ability to deliver certain amino acids that are relatively unstable or poorly soluble in aqueous solutions. These various aspects of intravenous dipeptides are considered in this review.
Authors:
J A Vazquez; H Daniel; S A Adibi
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition     Volume:  8     ISSN:  0884-5336     ISO Abbreviation:  Nutr Clin Pract     Publication Date:  1993 Jun 
Date Detail:
Created Date:  1994-02-24     Completed Date:  1994-02-24     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8606733     Medline TA:  Nutr Clin Pract     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  95-105     Citation Subset:  N    
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Proteins / analysis,  drug effects
Clinical Trials as Topic
Dipeptides / chemistry,  pharmacology,  therapeutic use*
Drug Evaluation, Preclinical
Humans
Parenteral Nutrition / methods*
Rats
Chemical
Reg. No./Substance:
0/Blood Proteins; 0/Dipeptides
Comments/Corrections
Comment In:
Nutr Clin Pract. 1993 Jun;8(3):93-4   [PMID:  8289764 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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