Document Detail

Dioxin, dibenzofuran, and polychlorinated biphenyl (PCB) levels in food from Agent Orange-sprayed and nonsprayed areas of Laos.
MedLine Citation:
PMID:  14710598     Owner:  NLM     Status:  MEDLINE    
During the Vietnam War, a phenoxy-herbicide mixture called Agent Orange, which was contaminated with 2,3,7,8-tetrachlorodibenzodioxin, or TCDD, was used primarily for destruction of forest and other foliage in order to prevent enemy troop movement and protect American and allied troops and military bases in the south of Vietnam. Smaller areas of Laos and Cambodia were also sprayed with Agent Orange between 1962 and 1971 from fixed-wing aircraft. In 2001, 28 food samples consisting of meat, fish, and dairy products were collected in sprayed and nonsprayed areas of Laos and analyzed for dioxins, dioxinlike dibenzofurans, and selected polychlorinated biphenyl (PCB) congeners by high-resolution gas chromatography/high-resolution mass spectrometry at laboratories in Germany and Canada. Low levels of dioxin and other dioxinlike substances were found in Laotian food, similar to levels present in recent exported Vietnamese food to United States. Vietnam is geographically adjacent to Laos. Total dioxin toxic equivalent (TEQ) levels were similar in samples from sprayed and non-sprayed areas, ranging from 0.009 to 0.851 pg/g or parts per trillion (ppt) in sprayed Sepone, and from 0.022 to 0.537 pg/g or ppt wet weight in non sprayed Vientiane. However, the Laotian fish samples from the Agent Orange-sprayed area had, on average, a higher proportion of total TEQ from TCDD (31.7% vs. 9.4%) compared to the nonsprayed area. Some other food items, duck eggs and pork liver from Sepone, also had severalfold higher TCDD levels than similar food samples from Vientiane, 0.029 vs. 0.011 pg/g and 0.070 vs. 0.004 pg/g wet weight, respectively. There were no substantial differences in levels of dibenzofuran and PCB congeners. In general, elevated TCDD levels were not found in Laotian food samples. It is possible that dioxin-contaminated areas, or "hot spots," exist in Laos as they do in Vietnam, although they have not yet been identified.
Arnold Schecter; Marian Pavuk; Rainer Malisch; John Jake Ryan
Related Documents :
18845308 - Pcbs in fish from the southern baltic sea: levels, bioaccumulation features, and tempor...
3928858 - An epidemic of precocious development in puerto rican children.
15276278 - Characterization of contaminants in snapping turtles (chelydra serpentina) from canadia...
11436818 - Pcbs and organochlorine pesticide residues in eggs of audouin's gull (larus audouinii) ...
24402968 - Implementing unpredictability in feeding enrichment for malayan sun bears (helarctos ma...
16711538 - Wheat flour allergy: an entire diagnostic tool for complex allergy.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of toxicology and environmental health. Part A     Volume:  66     ISSN:  1528-7394     ISO Abbreviation:  J. Toxicol. Environ. Health Part A     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2004-01-08     Completed Date:  2004-01-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100960995     Medline TA:  J Toxicol Environ Health A     Country:  England    
Other Details:
Languages:  eng     Pagination:  2165-86     Citation Subset:  IM    
University of Texas Health Science Center, School of Public Health, Dallas Regional Campus, Dallas, Texas, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
2,4,5-Trichlorophenoxyacetic Acid*
2,4-Dichlorophenoxyacetic Acid*
Benzofurans / analysis*
Dairy Products
Defoliants, Chemical*
Dioxins / analysis*
Environmental Monitoring
Environmental Pollutants / analysis*
Food Contamination*
Polychlorinated Biphenyls / analysis*
Reg. No./Substance:
0/Benzofurans; 0/Defoliants, Chemical; 0/Dioxins; 0/Environmental Pollutants; 0/Polychlorinated Biphenyls; 132-64-9/dibenzofuran; 1746-01-6/Tetrachlorodibenzodioxin; 39277-47-9/Agent Orange; 93-76-5/2,4,5-Trichlorophenoxyacetic Acid; 94-75-7/2,4-Dichlorophenoxyacetic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Pharmacokinetics/pharmacodynamics (PK/PD) modeling of risks of kidney toxicity from exposure to cadm...
Next Document:  Caries diagnosis: the lesions are central