Document Detail


Dinucleotide repeat (GT)n markers on chromosome 21.
MedLine Citation:
PMID:  1427915     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To further develop the linkage map of human chromosome 21 (HC21), we have concentrated on identifying highly polymorphic markers based on dinucleotide repeat sequences such as (GT)n, as these are often highly polymorphic, are widespread throughout the human genome, and can be rapidly analyzed by the polymerase chain reaction. We report here nine (GT)n polymorphic markers from HC21.
Authors:
A C Warren; M G McInnis; J Blaschak; M Kaliatsidaki; M B Petersen; A Chakravarti; S E Antonarakis
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Genomics     Volume:  14     ISSN:  0888-7543     ISO Abbreviation:  Genomics     Publication Date:  1992 Nov 
Date Detail:
Created Date:  1992-12-17     Completed Date:  1992-12-17     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8800135     Medline TA:  Genomics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  818-9     Citation Subset:  IM    
Affiliation:
Center for Medical Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.
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MeSH Terms
Descriptor/Qualifier:
Animals
Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 21*
DNA
Genetic Markers
Humans
Hybrid Cells
Mice
Molecular Sequence Data
Polymorphism, Genetic*
Repetitive Sequences, Nucleic Acid*
Grant Support
ID/Acronym/Agency:
HD24605/HD/NICHD NIH HHS; HG00373/HG/NHGRI NIH HHS
Chemical
Reg. No./Substance:
0/Genetic Markers; 9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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