| Dinoprostone vaginal insert versus intravenous oxytocin to reduce postpartum blood loss following vaginal or cesarean delivery. | |
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MedLine Citation:
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PMID: 20420283 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To compare the impact of a dinoprostone vaginal insert and intravenous oxytocin in reducing blood loss of women undergoing vaginal or cesarean delivery. METHODS: This study was conducted among term singleton pregnancies delivered vaginally or by elective cesarean section. In the vaginally delivered cases, active management of the third stage of labor was conducted. During cesarean delivery, 20 IU of intravenous oxytocin was administered. Women, who either delivered via the vaginal or abdominal route, were then randomly allocated to receive 10 mg vaginal dinoprostone insert for 12 hours (group I, n: 100) or intravenous oxytocin (group II, n: 100), respectively. RESULTS: Mean blood loss and need for additional uterotonics and postpartum hemoglobin and hematocrit levels at 24 and 36 hours after delivery did not differ between the two groups. Women allocated to the dinoprostone vaginal insert arm experienced more nausea and vomiting. CONCLUSION: Dinoprostone vaginal insert was as effective as intravenous oxytocin in the prevention of postpartum blood loss. |
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Authors:
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E Ozalp; H M Tanir; T Sener |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Clinical and experimental obstetrics & gynecology Volume: 37 ISSN: 0390-6663 ISO Abbreviation: Clin Exp Obstet Gynecol Publication Date: 2010 |
Date Detail:
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Created Date: 2010-04-27 Completed Date: 2010-06-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7802110 Medline TA: Clin Exp Obstet Gynecol Country: Italy |
Other Details:
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Languages: eng Pagination: 53-5 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Perinatology Unit, Eskisehir Osmangazi University School of Medicine, Meselik Kampusu, Eskisehir, Turkey. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Intravaginal Adult Delayed-Action Preparations Delivery, Obstetric Diarrhea / epidemiology Dinoprostone / therapeutic use* Female Fever / epidemiology Humans Infusions, Intravenous Nausea / epidemiology Oxytocics / therapeutic use* Oxytocin / therapeutic use* Postpartum Hemorrhage / prevention & control* Pregnancy Prospective Studies Shivering Vomiting / epidemiology |
| Chemical | |
Reg. No./Substance:
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0/Delayed-Action Preparations; 0/Oxytocics; 363-24-6/Dinoprostone; 50-56-6/Oxytocin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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