Document Detail


Dimethylformamide-induced occupational liver injury--a case report.
MedLine Citation:
PMID:  9819509     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Dimethylformamide(DMF), a widely used industrial solvent, has been reported to induce subtle to clinically overt hepatotoxicity. Liver injury due to occupational exposure through inhalation and skin contact have been sporadically reported. We reported a 42-year-old male Taiwanese who developed progressive, intermittent abdominal pain for 6 months after working in a synthetic leather factory. Acute hepatitis episode occurred after working in an enclosed and poorly-ventilated workplace for one day. Based on occupational history, pathological examination and serial liver function examinations, the case was compatible with DMF-induced acute chemical hepatitis.
Authors:
J F Huang; H T Kuo; C K Ho; T J Chen; W Y Chang
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Kaohsiung journal of medical sciences     Volume:  14     ISSN:  1607-551X     ISO Abbreviation:  Kaohsiung J. Med. Sci.     Publication Date:  1998 Oct 
Date Detail:
Created Date:  1998-12-17     Completed Date:  1998-12-17     Revised Date:  2006-08-28    
Medline Journal Info:
Nlm Unique ID:  100960562     Medline TA:  Kaohsiung J Med Sci     Country:  TAIWAN    
Other Details:
Languages:  eng     Pagination:  655-8     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Kaohsiung Medical College Hospital, Tainan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Dimethylformamide / adverse effects*
Humans
Liver / drug effects*,  pathology
Male
Occupational Exposure / adverse effects*
Chemical
Reg. No./Substance:
68-12-2/Dimethylformamide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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