Document Detail


Diltiazem: dose it affect vasospasm?
MedLine Citation:
PMID:  3523805     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Calcium antagonists are being investigated for their role in preventing or ameliorating the vasospasm associated with subarachnoid hemorrhage. We have done a phase I and phase II type trial of diltiazem. No effect on spasm was documented. A tendency to increase the bleeding time was noted, but no detrimental clinical effect occurred. The rebleed rate was not changed. It appears that further study of diltiazem through a proper randomized study would not be cost- or time-effective.
Authors:
F W Saunders; W J Marshall
Related Documents :
7509665 - Ventricular arrhythmias during exercise testing and daily activities in patients with s...
14559135 - Beneficial effects of betaxolol, a selective antagonist of beta-1 adrenoceptors, on exe...
7468415 - Aggravation of angina pectoris by two percent carboxyhemoglobin.
22335885 - The effects of splinting on shoulder function in adult burns.
11053325 - Initial ventilatory and circulatory responses to dynamic exercise are slowed in the eld...
15016635 - Exercise-induced and nitroglycerin-induced myocardial preconditioning improves hemodyna...
Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Surgical neurology     Volume:  26     ISSN:  0090-3019     ISO Abbreviation:  Surg Neurol     Publication Date:  1986 Aug 
Date Detail:
Created Date:  1986-08-08     Completed Date:  1986-08-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0367070     Medline TA:  Surg Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  155-8     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Benzazepines / therapeutic use*
Clinical Trials as Topic
Diltiazem / therapeutic use*
Humans
Ischemic Attack, Transient / drug therapy*
Random Allocation
Subarachnoid Hemorrhage / drug therapy
Chemical
Reg. No./Substance:
0/Benzazepines; 42399-41-7/Diltiazem

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Advances in the management of carcinoma of the breast.
Next Document:  Squamous cell carcinoma of the eyelid.