| Dilated cardiomyopathy due to thrombotic microangiopathy as the only manifestation of antiphospholipid syndrome: a case report. | |
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MedLine Citation:
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PMID: 18336752 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Dilated cardiomyopathy due to thrombotic microangiopathy has been rarely reported as a clinical manifestation of antiphospholipid syndrome (APS). We describe the case of a 39-year-old woman affected by systemic lupus erythematosus (SLE) and positive antiphospholipid antibodies (aPL) who presented with orthopnea and peripheral oedema. Diagnosis of dilated cardiomyopathy due to myocardial thrombotic microangiopathy was made and treatment with anticoagulants prevented the worsening of the clinical condition. Interestingly, at variance with other cases, our patient showed no extracardiac signs of APS. The review of the current literature has confirmed that dilated cardiomyopathy due to thrombotic microangiopathy is a rare manifestation of APS. |
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Authors:
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F Vaccaro; D Caccavo; E Roumpedaki; G De Vincentis; C R T Di Gioia; P Gallo; P Palange |
Publication Detail:
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Type: Case Reports; Letter; Review |
Journal Detail:
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Title: International journal of immunopathology and pharmacology Volume: 21 ISSN: 0394-6320 ISO Abbreviation: Int J Immunopathol Pharmacol Publication Date: 2008 Jan-Mar |
Date Detail:
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Created Date: 2008-03-13 Completed Date: 2008-06-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8911335 Medline TA: Int J Immunopathol Pharmacol Country: Italy |
Other Details:
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Languages: eng Pagination: 237-41 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antiphospholipid Syndrome / complications* Cardiomyopathy, Dilated / etiology* Coronary Circulation Female Humans Lupus Erythematosus, Systemic / complications* Microcirculation Thrombosis / complications* |
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