Document Detail

Dilated cardiomyopathy due to thrombotic microangiopathy as the only manifestation of antiphospholipid syndrome: a case report.
MedLine Citation:
PMID:  18336752     Owner:  NLM     Status:  MEDLINE    
Dilated cardiomyopathy due to thrombotic microangiopathy has been rarely reported as a clinical manifestation of antiphospholipid syndrome (APS). We describe the case of a 39-year-old woman affected by systemic lupus erythematosus (SLE) and positive antiphospholipid antibodies (aPL) who presented with orthopnea and peripheral oedema. Diagnosis of dilated cardiomyopathy due to myocardial thrombotic microangiopathy was made and treatment with anticoagulants prevented the worsening of the clinical condition. Interestingly, at variance with other cases, our patient showed no extracardiac signs of APS. The review of the current literature has confirmed that dilated cardiomyopathy due to thrombotic microangiopathy is a rare manifestation of APS.
F Vaccaro; D Caccavo; E Roumpedaki; G De Vincentis; C R T Di Gioia; P Gallo; P Palange
Publication Detail:
Type:  Case Reports; Letter; Review    
Journal Detail:
Title:  International journal of immunopathology and pharmacology     Volume:  21     ISSN:  0394-6320     ISO Abbreviation:  Int J Immunopathol Pharmacol     Publication Date:    2008 Jan-Mar
Date Detail:
Created Date:  2008-03-13     Completed Date:  2008-06-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8911335     Medline TA:  Int J Immunopathol Pharmacol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  237-41     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Antiphospholipid Syndrome / complications*
Cardiomyopathy, Dilated / etiology*
Coronary Circulation
Lupus Erythematosus, Systemic / complications*
Thrombosis / complications*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Parecoxib as an alternative in COX-2 hypersensitivity.
Next Document:  Sinus augmentation procedure of the jaw sinus in patients with mucocele.