Document Detail


Dilated cardiomyopathy due to thrombotic microangiopathy as the only manifestation of antiphospholipid syndrome: a case report.
MedLine Citation:
PMID:  18336752     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Dilated cardiomyopathy due to thrombotic microangiopathy has been rarely reported as a clinical manifestation of antiphospholipid syndrome (APS). We describe the case of a 39-year-old woman affected by systemic lupus erythematosus (SLE) and positive antiphospholipid antibodies (aPL) who presented with orthopnea and peripheral oedema. Diagnosis of dilated cardiomyopathy due to myocardial thrombotic microangiopathy was made and treatment with anticoagulants prevented the worsening of the clinical condition. Interestingly, at variance with other cases, our patient showed no extracardiac signs of APS. The review of the current literature has confirmed that dilated cardiomyopathy due to thrombotic microangiopathy is a rare manifestation of APS.
Authors:
F Vaccaro; D Caccavo; E Roumpedaki; G De Vincentis; C R T Di Gioia; P Gallo; P Palange
Publication Detail:
Type:  Case Reports; Letter; Review    
Journal Detail:
Title:  International journal of immunopathology and pharmacology     Volume:  21     ISSN:  0394-6320     ISO Abbreviation:  Int J Immunopathol Pharmacol     Publication Date:    2008 Jan-Mar
Date Detail:
Created Date:  2008-03-13     Completed Date:  2008-06-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8911335     Medline TA:  Int J Immunopathol Pharmacol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  237-41     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Antiphospholipid Syndrome / complications*
Cardiomyopathy, Dilated / etiology*
Coronary Circulation
Female
Humans
Lupus Erythematosus, Systemic / complications*
Microcirculation
Thrombosis / complications*

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