| Dilatation of the left ventricular cavity on dipyridamole thallium-201 imaging: a new marker of triple-vessel disease. | |
| | |
MedLine Citation:
|
PMID: 1990750 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
To investigate the significance and mechanism of dilatation of the left ventricular cavity on dipyridamole thallium-201 imaging, we performed both dipyridamole thallium-201 imaging and dipyridamole radionuclide angiography on 83 patients with known angiograms. The dipyridamole/delayed ratio of the left ventricular dimension from the thallium-201 image was defined as the left ventricular dilatation ratio (LVDR). An LVDR greater than the mean + two standard deviations in patients without coronary artery disease was defined as abnormal. Twenty-two of 83 patients showed an abnormal LVDR, and 18 of the 22 patients (82%) had triple-vessel disease. By defect and washout analysis, the sensitivity and specificity for correctly identifying the patients as having triple-vessel disease was 72% and 76%, respectively, whereas LVDR had a sensitivity of 72% and a specificity of 93%. When LVDR was used in combination with the defect and washout criteria, sensitivity increased to 84% without a loss of specificity. In those 22 patients with abnormal LVDRs, end-diastolic volume measured by radionuclide angiography did not change after dipyridamole infusion. Dilatation of the left ventricular cavity on dipyridamole thallium-201 imaging reflected relative subendocardial hypoperfusion induced by dipyridamole rather than actual chamber enlargement. The LVDR was moderately sensitive and highly specific for triple-vessel disease and provided complementary information to dipyridamole thallium-201 imaging. |
| | |
Authors:
|
Y Takeishi; I Tono-oka; K Ikeda; A Komatani; K Tsuiki; S Yasui |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: American heart journal Volume: 121 ISSN: 0002-8703 ISO Abbreviation: Am. Heart J. Publication Date: 1991 Feb |
Date Detail:
|
Created Date: 1991-03-06 Completed Date: 1991-03-06 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0370465 Medline TA: Am Heart J Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 466-75 Citation Subset: AIM; IM |
Affiliation:
|
First Department of Internal Medicine, Yamagata University School of Medicine, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Coronary Disease / physiopathology, radionuclide imaging* Dipyridamole / diagnostic use* Female Gated Blood-Pool Imaging* / methods Heart Catheterization Hemodynamics / physiology Humans Male Middle Aged Thallium Radioisotopes / diagnostic use* Vasodilation / drug effects*, physiology Ventricular Function, Left / drug effects*, physiology |
| Chemical | |
Reg. No./Substance:
|
0/Thallium Radioisotopes; 58-32-2/Dipyridamole |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Factors associated with recurrent myocardial infarction within one year after acute myocardial infar...
Next Document: Percutaneous balloon valvotomy for patients with mitral stenosis: initial and follow-up results.