| Dilantin-induced long-term bilateral total external ophthalmoplegia. | |
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MedLine Citation:
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PMID: 2939108 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A young, healthy woman underwent craniotomy for the resection of a corpus callosum arteriovenous malformation. She was slow to awaken from anesthesia and was later noted to have a total external ophthalmoplegia. Her mental status quickly improved but the total ophthalmoplegia showed only minimal improvement for 2 weeks. After ruling out possible cerebrovascular and anesthetic complications, we concluded that the oculomotor impairment was due to postoperative toxic levels of Dilantin. Toxic Dilantin levels are known to rarely produce total ophthalmoplegia. In previously reported cases, this has always resolved with normalization of the serum Dilantin levels. This case represents the first report of Dilantin-induced ophthalmoplegia that took at least 3 months to resolve; it provides a detailed documentation of the course of ocular findings. |
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Authors:
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C A Fredericks; S L Giannotta; A A Sadun |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of clinical neuro-ophthalmology Volume: 6 ISSN: 0272-846X ISO Abbreviation: J Clin Neuroophthalmol Publication Date: 1986 Mar |
Date Detail:
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Created Date: 1986-06-06 Completed Date: 1986-06-06 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8109051 Medline TA: J Clin Neuroophthalmol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 22-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cerebral Angiography Chronic Disease Corpus Callosum / surgery Female Humans Intracranial Arteriovenous Malformations / radiography, surgery Ophthalmoplegia / chemically induced*, pathology Phenytoin / administration & dosage, adverse effects*, blood Postoperative Period Premedication |
| Chemical | |
Reg. No./Substance:
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57-41-0/Phenytoin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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