Document Detail

Dilantin-induced long-term bilateral total external ophthalmoplegia.
MedLine Citation:
PMID:  2939108     Owner:  NLM     Status:  MEDLINE    
A young, healthy woman underwent craniotomy for the resection of a corpus callosum arteriovenous malformation. She was slow to awaken from anesthesia and was later noted to have a total external ophthalmoplegia. Her mental status quickly improved but the total ophthalmoplegia showed only minimal improvement for 2 weeks. After ruling out possible cerebrovascular and anesthetic complications, we concluded that the oculomotor impairment was due to postoperative toxic levels of Dilantin. Toxic Dilantin levels are known to rarely produce total ophthalmoplegia. In previously reported cases, this has always resolved with normalization of the serum Dilantin levels. This case represents the first report of Dilantin-induced ophthalmoplegia that took at least 3 months to resolve; it provides a detailed documentation of the course of ocular findings.
C A Fredericks; S L Giannotta; A A Sadun
Related Documents :
6097568 - The use of collagenase-clostridiopeptidase combined with chloramphenicol in orthopaedic...
8934798 - Minocycline-induced serum sickness.
24932258 - Primary carcinoma of the frontal sinus with extensive intracranial invasion: a case rep...
9663328 - Ergotism and vascular insufficiency: a case report and review of literature.
2037328 - Hand injuries from leading horses.
20212408 - Oral signs in the diagnosis of celiac disease: review of the literature.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical neuro-ophthalmology     Volume:  6     ISSN:  0272-846X     ISO Abbreviation:  J Clin Neuroophthalmol     Publication Date:  1986 Mar 
Date Detail:
Created Date:  1986-06-06     Completed Date:  1986-06-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8109051     Medline TA:  J Clin Neuroophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  22-6     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cerebral Angiography
Chronic Disease
Corpus Callosum / surgery
Intracranial Arteriovenous Malformations / radiography,  surgery
Ophthalmoplegia / chemically induced*,  pathology
Phenytoin / administration & dosage,  adverse effects*,  blood
Postoperative Period
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Correlative study of the computed tomographic, ultrasonographic, and pathological characteristics of...
Next Document:  Adult-onset cyclic esotropia and optic atrophy.