Document Detail

Dihydrocodeine: a useful tool in the detoxification of methadone-maintained patients.
MedLine Citation:
PMID:  11027902     Owner:  NLM     Status:  MEDLINE    
We investigated the merit of dihydrocodeine tartrate for withdrawal in detoxifying 20 methadone-maintained patients presenting for treatment at the Leeds Addiction Unit (LAU). Thirteen patients (65%) successfully completed methadone detoxification and were abstinent from both methadone and opiate-type drugs at the end of the 2-week program. On completion, three patients began treatment with Naltrexone and another was abstinent at a follow-up appointment, 1 week later. A further patient relapsed back to heroin use but remained in contact with the LAU. The remaining six patients dropped out of the 2-week detoxification program between days 3 and 11 of the dihydrocodeine cross-over period. We believe dihydrocodeine may have advantages in detoxifying methadone-maintained patients.
J Banbery; K Wolff; D Raistrick
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of substance abuse treatment     Volume:  19     ISSN:  0740-5472     ISO Abbreviation:  J Subst Abuse Treat     Publication Date:  2000 Oct 
Date Detail:
Created Date:  2000-11-20     Completed Date:  2000-11-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8500909     Medline TA:  J Subst Abuse Treat     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  301-5     Citation Subset:  IM    
Leeds Addiction Unit, 19 Springfield Mount, LS2 9NG, Leeds, UK.
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MeSH Terms
Analgesics, Opioid / administration & dosage*
Codeine / administration & dosage,  analogs & derivatives*
Cross-Over Studies
Dose-Response Relationship, Drug
Drug Administration Schedule
Methadone / administration & dosage*
Opioid-Related Disorders / rehabilitation*
Retrospective Studies
Treatment Outcome
Reg. No./Substance:
0/Analgesics, Opioid; 125-28-0/dihydrocodeine; 76-57-3/Codeine; 76-99-3/Methadone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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