Document Detail


Digitalis in pneumonectomy and its implication.
MedLine Citation:
PMID:  529326     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Between 1968 and 1977, 87 patients underwent pneumonectomy at Rhode Island Hospital. Postoperatively, 25 patients developed arrhythmia (29 percent), giving rise to hemodynamic deterioration necessitating aggressive treatment. There were nine hospital deaths (10 percent). The effect of preoperative digitalis was analyzed in 68 patients over age 50 years.In Group 1, digoxin was not used until the onset of arrhythmia. There were 40 patients in this group; 18 developed arrhythmia (45 percent) with four deaths (22 percent).In Group 2, patients were given digitalis preoperatively. There were 28 patients; six developed arrhythmia (21 percent) with no deaths.Thus, the high incidence (45 percent in Group 1 and 21 percent in Group 2), as well as risk of mortality (4/18 patients) from arrhythmia following pneumonectomy, in patients over 50 years of age without digitalization, is a strong indication for preoperative digitalis.
Authors:
O A Adebo; A K Singh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the National Medical Association     Volume:  71     ISSN:  0027-9684     ISO Abbreviation:  J Natl Med Assoc     Publication Date:  1979 Jul 
Date Detail:
Created Date:  1980-04-25     Completed Date:  1980-04-25     Revised Date:  2010-10-26    
Medline Journal Info:
Nlm Unique ID:  7503090     Medline TA:  J Natl Med Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  669-70     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Arrhythmias, Cardiac / etiology,  prevention & control*
Digitalis Glycosides / therapeutic use*
Digoxin / administration & dosage,  therapeutic use
Humans
Middle Aged
Pneumonectomy*
Postoperative Complications / prevention & control*
Chemical
Reg. No./Substance:
0/Digitalis Glycosides; 20830-75-5/Digoxin
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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