Document Detail

Digital pressure responses to cooling in patients with suspected early vs definite scleroderma (systemic sclerosis) vs primary Raynaud's phenomenon.
MedLine Citation:
PMID:  7983649     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare digital vascular responses to local finger cooling in 4 groups of subjects: patients with definite scleroderma (SD, systemic sclerosis) meeting ARA criteria (n = 16), patients with suspected early SD (n = 12), patients with primary Raynaud's phenomenon (RP) (n = 23) and a control group of 29 healthy subjects. METHODS: Their digital systolic pressures were measured at 30, 20, 15 and 10 degrees C finger cuff temperature, in a room kept at 18 degrees C. RESULTS: The results of the digital pressure measurements showed a clearcut difference between the SD, primary RP and control groups, but there was no difference between patients with definite SD and those with suspected early SD. CONCLUSION: Under our experimental conditions, digital pressure response to local cooling separates groups of patients with primary RP and those with secondary RP related to SD from each other and from controls. The similarity between digital pressure responses of patients with suspected early SD and those with definite SD, suggests an early organic involvement of the digital vasculature in SD.
H R Maricq; F Diat; M C Weinrich; J G Maricq
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of rheumatology     Volume:  21     ISSN:  0315-162X     ISO Abbreviation:  J. Rheumatol.     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1995-01-04     Completed Date:  1995-01-04     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  7501984     Medline TA:  J Rheumatol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  1472-6     Citation Subset:  IM    
Department of Medicine, Medical University of South Carolina, Charleston 29425.
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MeSH Terms
Arteries / physiopathology
Blood Pressure*
Case-Control Studies
Cold Temperature / diagnostic use*
Fingers / blood supply*
Middle Aged
Raynaud Disease / diagnosis*,  physiopathology
Scleroderma, Systemic / diagnosis*,  physiopathology
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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