Document Detail

Diflucortolone valerate (Nerisona): a comparative vasoconstriction test in artificially induced hyperemia of the skin.
MedLine Citation:
PMID:  7459929     Owner:  NLM     Status:  MEDLINE    
In 20 healthy volunteers of both sexes the vasoconstrictive activity of diflucortolone valerate in two of its commercially available formulations (water-in-oil emulsion and pure fat base) was compared with that of four other substances: fluocinonide; betamethasone-17,21-dipropionate; hydrocortisone-17-butyrate; and clobetasol-17-propionate in corresponding galenical formulations. The visual assessment of vasoconstrictive activity after 10 hours revealed a statistically significant superiority of diflucortolone valerate in its fat base over the corresponding galenical formulations of fluocinonide, clobetasol-17-propionate, and hydrocortisone-17-butyrate. Diflucortolone valerate in a water-in-oil emulsion was statistically better after eight hours than the cream formulations of fluocinonide; clobetasol-17-propionate, and betamethasone-17,21-dipropionate.
R Reckers; H Wendt
Related Documents :
18377789 - Trans fatty acids and cardiovascular risk: a unique cardiometabolic imprint?
15072929 - Proteins and emulsifiers at liquid interfaces.
9420189 - Contribution of trans fatty acids from vegetable oils and margarines to the belgian diet.
16646479 - Gaseous hexane biodegradation by fusarium solani in two liquid phase packed-bed and sti...
7459929 - Diflucortolone valerate (nerisona): a comparative vasoconstriction test in artificially...
15777439 - Relationship between dietary intake of cod liver oil in early pregnancy and birthweight.
17407909 - Sound pressure level and spectral balance linearity and symmetry in the messa di voce o...
20464439 - Stereotyping starlings are more 'pessimistic'.
15354159 - The youth/adolescent questionnaire has low validity and modest reliability among low-in...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Clinical therapeutics     Volume:  3     ISSN:  0149-2918     ISO Abbreviation:  Clin Ther     Publication Date:  1980  
Date Detail:
Created Date:  1981-04-24     Completed Date:  1981-04-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7706726     Medline TA:  Clin Ther     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  190-3     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Administration, Topical
Anti-Inflammatory Agents / pharmacology
Diflucortolone / analogs & derivatives*,  pharmacology
Fluocortolone / analogs & derivatives*
Regional Blood Flow / drug effects
Skin / blood supply*
Skin Tests
Vasoconstriction / drug effects*
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Glucocorticoids; 152-97-6/Fluocortolone; 2607-06-9/Diflucortolone; 59198-70-8/diflucortolone valerate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Quantitative effect of a single large dose of methylprednisolone on infarct size in baboons.
Next Document:  Allylestrenol: three years of experience with Gestanon in threatened abortion and premature labor.