| Diffusion-weighted magnetic resonance imaging in the differentiation of angiomyolipoma with minimal fat from clear cell renal cell carcinoma. | |
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MedLine Citation:
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PMID: 21815937 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of the present study was to evaluate diffusion-weighted (DW) magnetic resonance imaging (MRI) in differentiating between minimal fat angiomyolipoma (MFAML) and clear cell renal cell carcinoma (CCRCC). Forty-one solid renal tumors without visible macroscopic fat on unenhanced computed tomography images were evaluated by MRI, including DW-MRI, and were diagnosed pathologically as CCRCC (n = 36) or MFAML (n = 5). To evaluate the heterogeneity of diffusion in each tumor, the signals of the tumors on DW-MRI were analyzed subjectively and the apparent diffusion coefficient (ADC) values and histograms assessed objectively. Thirty-three of 36 CCRCC (92%) exhibited a heterogeneous signal on DW-MRI and several peaks in the ADC value histogram, whereas four of five MFAML exhibited a homogeneous signal on DW-MRI and a single prominent peak in the histogram. The standard deviations of the ADC values were significantly smaller for MFAML than for CCRCC (P = 0.0015). In conclusion, DW-MRI can be considered a useful and noninvasive addition to the preoperative differentiation of CCRCC and MFAML. |
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Authors:
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Hajime Tanaka; Soichiro Yoshida; Yasuhisa Fujii; Chikako Ishii; Hiroshi Tanaka; Fumitaka Koga; Kazutaka Saito; Hitoshi Masuda; Satoru Kawakami; Kazunori Kihara |
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Publication Detail:
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Type: Journal Article Date: 2011-08-04 |
Journal Detail:
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Title: International journal of urology : official journal of the Japanese Urological Association Volume: 18 ISSN: 1442-2042 ISO Abbreviation: Int. J. Urol. Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-09-21 Completed Date: 2012-01-23 Revised Date: 2012-02-06 |
Medline Journal Info:
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Nlm Unique ID: 9440237 Medline TA: Int J Urol Country: Australia |
Other Details:
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Languages: eng Pagination: 727-30 Citation Subset: IM |
Copyright Information:
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© 2011 The Japanese Urological Association. |
Affiliation:
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Department of Urology, Tokyo Medical and Dental University Graduate School, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adipose Tissue Adult Aged Angiomyolipoma / diagnosis*, pathology Carcinoma, Renal Cell / diagnosis* Diagnosis, Differential Diffusion Magnetic Resonance Imaging* Female Humans Kidney Neoplasms / diagnosis* Male Middle Aged Retrospective Studies |
| Comments/Corrections | |
Comment In:
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Int J Urol. 2012 Jan;19(1):90-1
[PMID:
22050376
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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