Document Detail

Diffusion-weighted imaging in chronic Behçet patients with and without neurological findings.
MedLine Citation:
PMID:  15918024     Owner:  NLM     Status:  MEDLINE    
Our aim was to investigate whether neurological impairment in chronic Behçet's disease (BD) patients with normal appearing brain can be assessed by means of diffusion-weighted imaging (DWI). The averaged apparent diffusion coefficient (ADC) values were calculated in 22 different radiologically normal appearing brain regions in 32 patients with and without neurological findings and 20 control subjects. The ADC values in bilateral frontal, temporal and occipital normal appearing white matter were significantly higher in the patient groups compared with the control subjects (p < 0.05). In these brain regions, DWI revealed differences in the ADC values between patients with neurological findings (including symptomatic and neuro-Behçet patients) and the asymptomatic patient group. The similarity of the ADC values of patients without symptoms to those of the control group allowed clear discrimination between patients with and without neurological findings. DWI may serve to assess subclinical neurological involvement in BD, even when structural changes are absent.
T Baysal; M Dogan; R Karlidag; H I Ozisik; O Baysal; T Bulut; K Sarac
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Publication Detail:
Type:  Journal Article     Date:  2005-05-26
Journal Detail:
Title:  Neuroradiology     Volume:  47     ISSN:  0028-3940     ISO Abbreviation:  Neuroradiology     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-07-15     Completed Date:  2006-01-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1302751     Medline TA:  Neuroradiology     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  431-7     Citation Subset:  IM    
Department of Radiology, Inonu University School of Medicine, Malatya, Turkey.
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MeSH Terms
Behcet Syndrome / complications*,  metabolism*,  pathology
Brain / metabolism*,  pathology
Case-Control Studies
Diffusion Magnetic Resonance Imaging
Middle Aged
Nervous System Diseases / etiology,  metabolism*,  pathology

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