Document Detail

Diffusion-weighted MRI predicts prognosis in severe hypoglycemic encephalopathy.
MedLine Citation:
PMID:  16815017     Owner:  NLM     Status:  MEDLINE    
A 20-year-old woman presented unconscious due to hypoglycemia after a self-administered insulin injection. Diffusion-weighted MRI (DWI), performed 5 days after admission, demonstrated heterogeneous high-intensity signal areas in both the cortex and subcortex but sparing the motor and sensory centers. On the 11th day after admission, she began making incomprehensible verbal sounds, eye opening spontaneously and moving her extremities with pyramidal tract signs. Three months later, she had aphasia, agnosia and apraxia but a normal gait without pyramidal tract signs or ataxia. DWI is thus considered useful to predict the functional outcome of patients with severe hypoglycemia.
Youichi Yanagawa; Naoaki Isoi; Aya M Tokumaru; Toshihisa Sakamoto; Yoshiaki Okada
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2006-07-11
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  13     ISSN:  0967-5868     ISO Abbreviation:  J Clin Neurosci     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-07-24     Completed Date:  2006-10-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  696-9     Citation Subset:  IM    
Department of Traumatology and Critical Care Medicine, National Defense Medical College, 3-1 Tokorozawa, Saitama 359-8513, Japan.
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MeSH Terms
Diffusion Magnetic Resonance Imaging*
Disease Progression
Hypoglycemia / chemically induced,  complications*
Insulin / administration & dosage
Neurotoxicity Syndromes / diagnosis*
Predictive Value of Tests
Self Administration
Reg. No./Substance:

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