| Diffusion-weighted MRI in the characterization of cystic pancreatic lesions: usefulness of ADC values. | |
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MedLine Citation:
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PMID: 20864287 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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PURPOSE: To evaluate the usefulness of diffusion-weighted magnetic resonance imaging (DW-MRI) in the differentiation of cystic pancreatic lesions. MATERIALS AND METHODS: Institutional review board approval was obtained, and written informed consent was taken from all enrolled subjects. Fifty-four patients with cystic pancreatic lesions of at least 1 cm in diameter (range:10-96 mm) at ultrasonography and/or computed tomography and 10 normal subjects underwent MRI at 1.5 T. These subjects included thirty-four patients with intraductal papillary mucinous tumors (IPMTs), 10 with pseudocysts, 5 with serous cystoadenoma and 5 with mucinous cystoadenoma. The MR protocol included axial T1w and T2w sequences and coronal MR cholangiopancreatography images. DW-MRI was performed using a breath-hold single-shot echo-planar sequence with a b gradient factor value of 500 s/mm(2) in the three orthogonal axes. Apparent diffusion coefficient (ADC) was calculated for cerebrospinal fluid, normal pancreatic parenchyma, and for each focal pancreatic lesion. Imaging results were correlated with endoscopic retrograde cholangiopancreatography, endoscopic ultrasound-guided fine needle aspiration, surgery and/or imaging follow-up. RESULTS: Mean ADC value was 4.1×10(-3) mm(2)/s for cerebrospinal fluid, 1.73×10(-3) mm(2)/s for normal pancreatic parenchyma, 4.09×10(-3) mm(2)/s for IPMT, 3.89×10(-3) mm(2)/s for mucinous cystoadenoma, 3.65×10(-3) mm(2)/s for serous cystoadenoma and 2.83×10(-3) mm(2)/s for pseudocyst. Mean ADC values of each of the different types of pancreatic lesions were statistically different (P<.05). CONCLUSION: DW-MRI may be helpful in the differential diagnosis of cystic pancreatic lesions. |
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Authors:
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Piero Boraschi; Francescamaria Donati; Roberto Gigoni; Simonetta Salemi; Carlo Bartolozzi; Fabio Falaschi |
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Publication Detail:
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Type: Journal Article Date: 2010-09-22 |
Journal Detail:
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Title: Magnetic resonance imaging Volume: 28 ISSN: 1873-5894 ISO Abbreviation: Magn Reson Imaging Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8214883 Medline TA: Magn Reson Imaging Country: Netherlands |
Other Details:
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Languages: eng Pagination: 1447-55 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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2nd Department of Radiology, Pisa University Hospital, 56124 Pisa, Italy. p.boraschi@do.med.unipi.it |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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