Document Detail

Diffusion tensor imaging of white matter tracts in the dog brain.
MedLine Citation:
PMID:  23355519     Owner:  NLM     Status:  In-Data-Review    
Diffusion weighted imaging sequences are now widely available on Magnetic Resonance Imaging (MRI) scanners. Diffusion Tensor Imaging (DTI) of the brain is able to show white matter tracts and is now commonly used in human medicine to study brain anatomy, tumors, structural pathways,… The purpose of this study was to show the interest of DTI to reveal the white matter fibers in the dogs' brain. DTI MR Images for this study were obtained with a 3 T system of 4 dogs euthanized for other reasons than neurological disorders. Combined fractional anisotropic (FA) and directional maps were obtained in the first 2 hours after death. The heads were amputated immediately after scanning and stored in 10% formalin until preparation for dissection. An experienced anatomist tracked white matter tracts with clinical relevance using the scanner software. The selected tracts were REFVIDume rendered and correlated with gross dissection. Using DTI we were able to track relevant neurological connections, such as the corticospinal tract, the optic and the cerebellar tract. The three dimensional anatomy is better presented using modern visualization techniques. DTI seems to be a valuable tool in order to present clinically relevant white matter tracts to neurological clinicians and researchers. Anat Rec, 296:340-349, 2013. © 2013 Wiley Periodicals, Inc.
Olivier Jacqmot; Bert Van Thielen; Yves Fierens; Martha Hammond; Inneke Willekens; Peter Van Schuerbeek; Filip Verhelle; Peter Goossens; Filip De Ridder; Jan Pieter Clarys; Anne Vanbinst; Johan De Mey
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anatomical record (Hoboken, N.J. : 2007)     Volume:  296     ISSN:  1932-8494     ISO Abbreviation:  Anat Rec (Hoboken)     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101292775     Medline TA:  Anat Rec (Hoboken)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  340-9     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Wiley Periodicals, Inc.
Department of Radiology, University Hospital Brussels, Morpho - Veterinary - Imaging (MOVE - IM BRUSSELS A.S.B.L.), UZ Brussel, Brussels, Belgium.
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