| Diffusion tensor imaging and its application to neuropsychiatric disorders. | |
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MedLine Citation:
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PMID: 12485979 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Magnetic resonance diffusion tensor imaging (DTI) is a new technique that can be used to visualize and measure the diffusion of water in brain tissue; it is particularly useful for evaluating white matter abnormalities. In this paper, we review research studies that have applied DTI for the purpose of understanding neuropsychiatric disorders. We begin with a discussion of the principles involved in DTI, followed by a historical overview of magnetic resonance diffusion-weighted imaging and DTI and a brief description of several different methods of image acquisition and quantitative analysis. We then review the application of this technique to clinical populations. We include all studies published in English from January 1996 through March 2002 on this topic, located by searching PubMed and Medline on the key words "diffusion tensor imaging" and "MRI." Finally, we consider potential future uses of DTI, including fiber tracking and surgical planning and follow-up. |
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Authors:
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Marek Kubicki; Carl-Fredrik Westin; Stephan E Maier; Hatsuho Mamata; Melissa Frumin; Hal Ersner-Hershfield; Ron Kikinis; Ferenc A Jolesz; Robert McCarley; Martha E Shenton |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: Harvard review of psychiatry Volume: 10 ISSN: 1067-3229 ISO Abbreviation: Harv Rev Psychiatry Publication Date: 2002 Nov-Dec |
Date Detail:
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Created Date: 2002-12-17 Completed Date: 2003-04-15 Revised Date: 2011-08-01 |
Medline Journal Info:
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Nlm Unique ID: 9312789 Medline TA: Harv Rev Psychiatry Country: United States |
Other Details:
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Languages: eng Pagination: 324-36 Citation Subset: IM |
Affiliation:
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Clinical Neuroscience Division, Laboratory of Neuroscience, Boston VA Health Care System-Brockton Division, Mass 02301, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anisotropy Brain / pathology Diffusion Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging / methods* Mental Disorders / diagnosis*, pathology Nervous System Diseases / diagnosis*, pathology |
| Grant Support | |
ID/Acronym/Agency:
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K02 MH 01110/MH/NIMH NIH HHS; K02 MH001110-06/MH/NIMH NIH HHS; P41 RR 13218/RR/NCRR NIH HHS; P41 RR013218-02/RR/NCRR NIH HHS; R01 MH 40799/MH/NIMH NIH HHS; R01 MH 50747/MH/NIMH NIH HHS; R01 MH040799-13/MH/NIMH NIH HHS; R01 MH050740-06/MH/NIMH NIH HHS; R01 NS 39335/NS/NINDS NIH HHS; R01 NS039335-01A1/NS/NINDS NIH HHS; R01 RR 11747/RR/NCRR NIH HHS; R01 RR011747-02/RR/NCRR NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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