Document Detail


Diffusion tensor imaging in refractory epilepsy.
MedLine Citation:
PMID:  12049867     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Diffusion tensor imaging is an imaging method that is sensitive to the molecular movement of water, which indicates cellular integrity and pathology. A patient with refractory epilepsy and normal conventional MRI was examined with diffusion tensor imaging. An area of abnormal diffusion in the right frontal lobe was identified and surgically resected. The patient had a good clinical outcome. Histopathological examination of the resected tissue showed gliosis. Our findings may affect the investigation of similar patients, and provide histopathological confirmation of diffusion abnormalities.
Authors:
Fergus J Rugg-Gunn; Sofia H Eriksson; Mark R Symms; Gareth J Barker; Maria Thom; William Harkness; John S Duncan
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Lancet     Volume:  359     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  2002 May 
Date Detail:
Created Date:  2002-06-06     Completed Date:  2002-06-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  England    
Other Details:
Languages:  eng     Pagination:  1748-51     Citation Subset:  AIM; IM    
Affiliation:
MRI Unit, National Society for Epilepsy and Research Department of Clinical and Experimental Epilepsy, Institute of Neurology, London, UK.
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MeSH Terms
Descriptor/Qualifier:
Adult
Electroencephalography
Epilepsy / diagnosis,  pathology*,  surgery
Female
Humans
Magnetic Resonance Imaging / methods*
Postoperative Period

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