| Diffusion tensor imaging in carpal tunnel syndrome. | |
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MedLine Citation:
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PMID: 21960133 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE: We aimed to investigate the efficacy of diffusion tensor imaging in the diagnosis of carpal tunnel syndrome and to obtain a quantitative parameter that may contribute to the diagnosis. MATERIALS AND METHODS: The median nerves in 57 wrists of 38 patients diagnosed as carpal tunnel syndrome and 30 wrists of 24 normal subjects were prospectively evaluated with a 3T Philips scanner, using standard 8-channel SENSE head coil. Diffusion tensor imaging was performed using spin echo-echo planar imaging. For anatomical reference, a T1-weighted sequence was acquired. Fractional anisotropy and apparent diffusion coefficient measurements were done focally at the carpal tunnel level and from whole median nerve. RESULTS: In carpal tunnel syndrome patients, both focal carpal tunnel and whole nerve measurements demonstrated statistically significantly lower fractional anisotropy values than normal subjects (P < 0.001). No statistically significant difference was observed in apparent diffusion coefficient measurements. The cut-off value obtained by receiver operator characteristics analysis was 0.554 for focal carpal tunnel fractional anisotropy (sensitivity, 80%; specificity, 80%) and 0.660 for whole nerve fractional anisotropy (sensitivity, 82%; specificity, 80%) measurement. CONCLUSION: Diffusion tensor imaging may contribute to the diagnosis of carpal tunnel syndrome on the basis of fractional anisotropy measurements. |
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Authors:
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Neslihan Tasdelen; Bengi Gurses; Ozgur Kilickesmez; Zeynep Firat; Geysu Karlikaya; Mustafa Tercan; Aziz Mufit Ulug; Ahmet Nevzat Gurmen |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-29 |
Journal Detail:
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Title: Diagnostic and interventional radiology (Ankara, Turkey) Volume: - ISSN: 1305-3612 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101241152 Medline TA: Diagn Interv Radiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Radiology, Yeditepe University School of Medicine, Istanbul, Turkey. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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