| Diffusion Tensor Imaging and Tractography of the Corticospinal Tract in the Presence of Enlarged Virchow-Robin Spaces. | |
| | |
MedLine Citation:
|
PMID: 22082139 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
BACKGROUND AND PURPOSE: We report a patient with abnormal diffusion tensor imaging (DTI) and tractography of the corticospinal tract caused by mass effect from adjacent enlarged Virchow-Robin spaces. METHODS: DTI was performed using 25 noncollinear directions. Fractional anisotropy (FA) and mean diffusivity (MD) maps were generated. Region-of-interest measurements of the corticospinal tracts were organized in histograms, and comparisons were made between sides. Statistical analysis consisted of a Wilcoxon rank-sum nonparametric test and a two-sample test of proportions to compare the relative percentage of voxels >.8. RESULTS: The patient had no signs or symptoms of motor weakness. The corticospinal tract adjacent to the enlarged Virchow-Robin spaces showed significant changes in the proportion of FA > .8, distribution of FA and distribution of MD (P < .001). CONCLUSIONS: Diffusion tensor changes may be caused by enlarged Virchow-Robin spaces in the absence of clinical signs or symptoms. We hypothesize that the DTI changes are due to alterations in the extravascular extracellular space. Tensor changes should be interpreted with caution in patients with space occupying mass lesions such as brain tumors. J Neuroimaging 2011;XX:1-4. |
| | |
Authors:
|
Robert J Young; Valerie Lee; Kyung K Peck; Tania Sierra; Zhigang Zhang; Lindsay M Jacks; Andrei I Holodny |
Related Documents
:
|
22038149 - Epileptogenic brain lesions in children: the added-value of combined diffusion imaging ... 22204209 - Acute vertebral compression fracture: differentiation of malignant and benign causes by... 21953599 - Direct mr arthrography of cadaveric wrists: comparison between mr imaging at 3.0t and 7... 22035159 - Papillary muscle dyssynchrony in patients with systolic left ventricular dysfunction. 19163579 - Mutual information driven inverse consistent nonlinear registration. 21956489 - The clinical value of fluorine-18 fluorodeoxyglucose positron emission tomography/compu... 8689819 - Pictorial review: radiology of the masticator space. 14736679 - Low mechanical index contrast-enhanced sonographic findings of pyogenic hepatic abscesses. 21401939 - Anal infections with concomitant chlamydia trachomatis genotypes among men who have sex... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-11-14 |
Journal Detail:
|
Title: Journal of neuroimaging : official journal of the American Society of Neuroimaging Volume: - ISSN: 1552-6569 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
|
Created Date: 2011-11-15 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9102705 Medline TA: J Neuroimaging Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
© 2011 by the American Society of Neuroimaging. |
Affiliation:
|
From the Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY (RJY, VL, KKP, TS, AH); Department of Epidemiology & Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY (ZZ, LmJ). |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Maternal effects and heritability of annual productivity.
Next Document: On the validity of the likelihood ratio test and consistency of resulting parameter estimates in joi...