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Diffusion tensor imaging of chronic right cerebral hemisphere infarctions.
MedLine Citation:
PMID:  20977525     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVE: We describe the essential diffusion tensor imaging (DTI) findings of right cerebral hemisphere infarctions and study whether the DTI parameters and neurological status differ in patients with visible wallerian degeneration (WD) or small hemorrhagic transformation (HT) in the chronic stage.
METHODS: Twenty-five stroke patients underwent DTI. Fractional anisotropy (FA) and mean diffusivity (MD) were measured in the infarction area, its corresponding contralateral area and both hemispheres in the centrum semiovale, cerebral peduncle, thalamus, internal capsule, and in corpus callosum genu, truncus, and splenium. The neurological scores were assessed in the acute and chronic phase. The subgroup analysis of WD and HT was conducted.
RESULTS: MD was higher in the right hemisphere (all P-values < .05), except on the internal capsule. FA was decreased in the infarction site, right cerebral peduncle, and centrum semiovale compared to the left side (P < .05). The chronic Rankin Scale was worse in the WD group. Their DTI parameters were different in 3 locations compared to patients with no WD. The HT group received fewer points in the chronic Barthel Index, and they had lower FA in the thalami.
CONCLUSIONS: DTI reveals the changes after infarction in the lesion site and elsewhere. The patients with visible WD or HT have more changes in the DTI parameters and worse outcome scores.
Authors:
Eeva Jason; Prasun Dastidar; Antti Kalliokoski; Tiina Luukkaala; Seppo Soimakallio
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Publication Detail:
Type:  Journal Article     Date:  2010-10-26
Journal Detail:
Title:  Journal of neuroimaging : official journal of the American Society of Neuroimaging     Volume:  21     ISSN:  1552-6569     ISO Abbreviation:  J Neuroimaging     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9102705     Medline TA:  J Neuroimaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  325-31     Citation Subset:  IM    
Copyright Information:
© 2010 by the American Society of Neuroimaging.
Affiliation:
From the Imaging Center of the Pirkanmaa Hospital District, Department of Diagnostic Radiology, Tampere University Hospital, Tampere, Finland (EJ, PD, AK, SS); Tampere Medical School, Tampere, Finland (EJ, PD, SS); and Science Center, Pirkanmaa Hospital District and Tampere School of Public Health, University of Tampere, Tampere, Finland (TL).
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