Document Detail

Diffuse smooth muscle proliferation of the lungs with severe pulmonary hypertension.
MedLine Citation:
PMID:  8816894     Owner:  NLM     Status:  MEDLINE    
We describe the second example of a distinctive clinicopathologic syndrome of severe pulmonary hypertension and interstitial lung disease caused by diffuse smooth muscle proliferation of the lungs (DSMPL) occurring in a 44-year-old man of normal intelligence with no cutaneous or neurological lesions. The smooth muscle proliferation involved the walls of bronchioles, alveoli, small pulmonary arteries, and pulmonary veins. DSMPL is distinct from pulmonary lymphangioleiomyomatosis and tuberous sclerosis, and does not appear to be neoplastic or reactive. The lesions are probably best regarded as multiple hamartomas or "native benign nodular smooth muscle proliferations."
J M Kay; L M Kahana; C Rihal
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Human pathology     Volume:  27     ISSN:  0046-8177     ISO Abbreviation:  Hum. Pathol.     Publication Date:  1996 Sep 
Date Detail:
Created Date:  1996-11-29     Completed Date:  1996-11-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9421547     Medline TA:  Hum Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  969-74     Citation Subset:  IM    
Department of Pathology, St. Joseph's Hospital, Hamilton Civic Hospitals, Ontario, Canada.
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MeSH Terms
Cell Division
Hypertension, Pulmonary / pathology*,  physiopathology,  radiography
Lung Diseases, Interstitial / pathology*,  physiopathology,  radiography
Muscle, Smooth / pathology*

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