Document Detail

Diffuse pulmonary opacification in infants undergoing extracorporeal membrane oxygenation: clinical and pathologic correlation.
MedLine Citation:
PMID:  3763898     Owner:  NLM     Status:  MEDLINE    
Diffuse pulmonary opacification is commonly seen on chest radiographs from infants with severe respiratory failure treated with extracorporeal membrane oxygenation (ECMO). The chest radiographs and clinical records of 18 such infants were reviewed to determine the correlation among degree of abnormality on chest radiograph (as determined by a radiographic score), clinical severity of disease (as measured by ECMO requirements [ECMO flow rate]), and dynamic lung compliance determinations. Increasing lung compliance and decreasing ECMO flow rates correlated well with decreasing (improving) radiographic score. Pathologic changes were mainly those associated with intensive respiratory support and the underlying pulmonary condition. One patient had diffuse pulmonary hemorrhage. Other than bleeding, no distinctive pathologic features could be attributed to therapy with ECMO. We conclude that the degree of pulmonary opacification seen in infants undergoing ECMO therapy is an accurate reflection of markedly decreased lung compliance and lung volumes caused by hyaline membrane formation, pulmonary edema, and atelectasis associated with the various causes of severe respiratory failure.
G A Taylor; A Lotze; S Kapur; B L Short
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiology     Volume:  161     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1986 Nov 
Date Detail:
Created Date:  1986-11-20     Completed Date:  1986-11-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  347-50     Citation Subset:  AIM; IM    
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MeSH Terms
Extracorporeal Circulation
Respiratory Insufficiency / pathology,  radiography*,  therapy

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