Document Detail


Diffuse liver metastasis of small cell lung cancer causing marked hepatomegaly and fulminant hepatic failure.
MedLine Citation:
PMID:  20647652     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
A 62-year-old female was admitted for examination of an abnormal liver function. Plain CT and MRI of the abdomen showed marked hepatomegaly but no visible nodular lesion in the liver. On the 3rd hospital day she had hepatic encephalopathy and was treated with a course of high-dose steroids, but ultimately died of disease progression on the 7th hospital day. An autopsy revealed a small pulmonary nodule with the histological findings showing small cell carcinoma. There was almost complete parenchymal replacement with metastatic tumor in the liver. Neoplastic involvement of the liver should be considered in the differential diagnosis of fulminant hepatic failure of unknown etiology.
Authors:
Hisamitsu Miyaaki; Tatsuki Ichikawa; Naota Taura; Mio Yamashima; Hideyuki Arai; Yoko Obata; Akira Furusu; Hiroko Hayashi; Shigeru Kohno; Kazuhiko Nakao
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-07-15
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  49     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2010  
Date Detail:
Created Date:  2010-07-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1383-6     Citation Subset:  IM    
Affiliation:
Department of Gastroenterology and Hepatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan. miyaaki-hi@umin.ac.jp
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