| Diffuse infantile haemangiomatosis: clinicopathological features and management problems in five fatal cases. | |
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MedLine Citation:
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PMID: 1843615 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The clinicopathological features of five fatal cases of diffuse haemangiomatosis presenting in neonatal life or early infancy are presented. The infants all had multiple skin haemangiomas as well as deep-seated lesions in many different tissues that caused protean clinical manifestations and management problems. Because the outlook may be improved by early diagnosis and application of new modes of treatment, any infant with multiple cutaneous haemangiomas should be closely assessed for possible visceral involvement. Development of hepatomegaly, high-output cardiac failure, unexplained anaemia or thrombocytopenia in these infants should immediately suggest disseminated disease. Early recognition with implementation of steroid and/or antiangiogenic therapy, embolization and/or surgery is essential to improve the chances of survival. |
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Authors:
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R W Byard; P E Burrows; T Izakawa; M M Silver |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: European journal of pediatrics Volume: 150 ISSN: 0340-6199 ISO Abbreviation: Eur. J. Pediatr. Publication Date: 1991 Feb |
Date Detail:
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Created Date: 1991-06-20 Completed Date: 1991-06-20 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7603873 Medline TA: Eur J Pediatr Country: GERMANY |
Other Details:
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Languages: eng Pagination: 224-7 Citation Subset: IM |
Affiliation:
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Department of Pathology, Hospital for Sick Children, University of Toronto, Ontario, Canada. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Hemangioma* / pathology, therapy Hemangioma, Cavernous / pathology, therapy Humans Infant Infant, Newborn Male Skin Neoplasms* / pathology, therapy |
| Comments/Corrections | |
Comment In:
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Eur J Pediatr. 1992 May;151(5):389
[PMID:
1396900
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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