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Diffuse cutaneous mastocytosis with generalized bullae.
MedLine Citation:
PMID:  20548889     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
We report on a 9-month-old female infant with multiple tense bullae and erosions covering the entire body, including the face, scalp, and trunk. The histopathological examination revealed sub-epidermal bullae with a dense dermal cellular infiltrate. The infiltrate was identified as a collection of mast cells using toluidine blue and Giemsa stains. The direct immunofluorscence was negative. A diagnosis of cutaneous diffuse mastocytosis with generalized bullae was made based on these clinical and histopathological findings. In cases with diffuse cutaneous mastocytosis with generalized bullae, systemic involvement is more frequent and more severe compared to other types of cutaneous mastocytosis. Some lethal outcomes have been reported. This is the first reported case of diffuse cutaneous mastocytosis in the Korean literature.
Authors:
Eui Hyung Lee; Mi Ri Kim; Tae Won Kang; Soo-Chan Kim
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Publication Detail:
Type:  Journal Article     Date:  2010-02-28
Journal Detail:
Title:  Annals of dermatology     Volume:  22     ISSN:  2005-3894     ISO Abbreviation:  Ann Dermatol     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-06-15     Completed Date:  2011-07-14     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  8916577     Medline TA:  Ann Dermatol     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  77-80     Citation Subset:  -    
Affiliation:
Department of Dermatology and the Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
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