| Diffuse choroidal haemangioma in Sturge-Weber syndrome treated with photodynamic therapy under general anaesthesia. | |
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MedLine Citation:
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PMID: 15702328 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To report the treatment outcome of photodynamic therapy with verteporfin (PDT) for exudative retinal detachment associated with diffuse choroidal haemangioma in Sturge-Weber syndrome. METHODS: An interventional case report of a 12-year-old girl with Sturge-Weber syndrome who developed an exudative retinal detachment (visual acuity 20/400) that was treated with PDT under general anaesthesia. PDT was performed according to the standard (macular degeneration) protocol, using three nonoverlapping spots of 4,000 microm. RESULTS: Subretinal fluid resolved completely over a period of 5 months and visual acuity increased to 20/50. No side effects of the PDT treatment were encountered during 9 months' follow-up. CONCLUSION: In our patient PDT with verteporfin effectively resolved the exudative retinal detachment associated with a diffuse choroidal haemangioma. Resolution of subretinal fluid occurred over several months without retreatment. We noted no side effects of the combination PDT and general anaesthesia, nor did we encounter ocular side effects of the treatment. |
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Authors:
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E A Huiskamp; R P H M Müskens; A Ballast; J M M Hooymans |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2005-02-09 |
Journal Detail:
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Title: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie Volume: 243 ISSN: 0721-832X ISO Abbreviation: Graefes Arch. Clin. Exp. Ophthalmol. Publication Date: 2005 Jul |
Date Detail:
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Created Date: 2005-07-04 Completed Date: 2005-12-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8205248 Medline TA: Graefes Arch Clin Exp Ophthalmol Country: Germany |
Other Details:
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Languages: eng Pagination: 727-30 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, University Hospital Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands. r.p.h.m.muskens@ohk.umcg.nl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anesthesia, General
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methods* Child Choroid Neoplasms / complications, drug therapy*, ultrasonography Exudates and Transudates Female Hemangioma / complications, drug therapy*, ultrasonography Humans Photochemotherapy* Photosensitizing Agents / therapeutic use Porphyrins / therapeutic use Retinal Detachment / drug therapy* Sturge-Weber Syndrome / complications, drug therapy* Tomography, Optical Coherence Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Photosensitizing Agents; 0/Porphyrins; 129497-78-5/verteporfin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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