Document Detail


Diffuse and broad podocytic detachment in a case of nephrotic syndrome associated with Kimura's disease.
MedLine Citation:
PMID:  8107312     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a 49-year-old Japanese male with nephrotic syndrome associated with Kimura's disease. Renal biopsy revealed diffuse podocytic detachment from the glomerular basement membrane (GBM). He had an episode of nephrotic syndrome when complete remission was induced with steroid therapy six years prior to the present admission. However, complete remission of the nephrotic syndrome was not achieved by the steroid on this admission and massive proteinuria (5 g/day) persisted. We suggest that steroid-resistant proteinuria is closely related to podocytic detachment from the GBM and that the production of extracellular matrix by epithelial cells may participate in segmental sclerotic lesions in the patient.
Authors:
T Moriya; T Shinoda; Y Kannou; K Nakajima; T Takeda; N Takasu; T Aizawa; T Yamada; Y Hataya; N Itoh
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Nihon Jinzo Gakkai shi     Volume:  36     ISSN:  0385-2385     ISO Abbreviation:  Nihon Jinzo Gakkai Shi     Publication Date:  1994 Jan 
Date Detail:
Created Date:  1994-03-22     Completed Date:  1994-03-22     Revised Date:  2011-08-01    
Medline Journal Info:
Nlm Unique ID:  7505731     Medline TA:  Nihon Jinzo Gakkai Shi     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  69-75     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
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MeSH Terms
Descriptor/Qualifier:
Angiolymphoid Hyperplasia with Eosinophilia / complications*
Basement Membrane / ultrastructure
Humans
Kidney Glomerulus / ultrastructure*
Male
Middle Aged
Nephrotic Syndrome / etiology*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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