Document Detail


Diffuse arterial thrombosis in a young man with elevated lipoprotein(a) and minimal atherosclerosis.
MedLine Citation:
PMID:  7780711     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An increased incidence of premature atherosclerotic arterial occlusive disease was recently reported in young adults. This condition is characterized by early occurrence of severe symptoms, lower incidence of typical cardiovascular risk factors for atherosclerosis, different natural course of arterial disease vis-a-vis older population, and poor outcome of a standard treatment. This report describes a young man with aggressive arterial occlusive disease in the lower extremities and symptom-free occlusions of coronary and renal arteries in association with high levels of lipoprotein(a). Microscopic early atherosclerotic changes were noted in the occluded arteries of the amputated leg. Premature atherosclerotic arterial occlusive disease in young adults has different clinical and pathological patterns, necessitating a different approach for evaluation and treatment.
Authors:
P J Levy; F Gonzalez; D Sheridan; J Carter; J L Haynes
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cardiovascular surgery (London, England)     Volume:  3     ISSN:  0967-2109     ISO Abbreviation:  Cardiovasc Surg     Publication Date:  1995 Feb 
Date Detail:
Created Date:  1995-07-14     Completed Date:  1995-07-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9308765     Medline TA:  Cardiovasc Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  56-9     Citation Subset:  IM    
Affiliation:
Department of Surgery, University of South Carolina, Richland Memorial Hospital, Columbia, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Amputation
Arterial Occlusive Diseases / complications*,  pathology
Arteriosclerosis / complications*,  pathology
Coronary Thrombosis / etiology*
Gangrene / etiology,  surgery
Humans
Hyperlipoproteinemias / complications*
Leg / blood supply
Lipoprotein(a) / blood*
Male
Renal Artery
Thrombosis / etiology
Chemical
Reg. No./Substance:
0/Lipoprotein(a)

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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