Document Detail


Diffuse amyloid deposition in thyroid gland: a cause for concern in familial Mediterranean fever.
MedLine Citation:
PMID:  22663145     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Thyroid gland is among the many organs that could be infiltrated in systemic amyloidosis. However, diffuse infiltration of the thyroid gland secondary to systemic amyloidosis associated with Familial Mediterranean fever (FMF) is rare. Here, we present a 49-year-old woman diagnosed with FMF and systemic amyloidosis, who had a large goiter and multiple nodules that developed slowly through the years and was complicated by tracheal compression symptoms and a mild thyroid dysfunction. Multiple fine needle aspiration biopsies of the nodules and the thyroid parenchyma revealed amyloid deposits. We would like to point out that amyloidosis may have a significant impact on the thyroid gland and fine needle aspiration biopsy is a valuable tool for diagnosis.
Authors:
Ozlem Turhan İyidir; Mustafa Altay; Ceyla Konca Degertekin; Alev Altınova; Ayhan Karakoç; Göksun Ayvaz; Metin Arslan; Kürşad Oneç; Turgay Arınsoy; Nesibe Cesur; Ipek Işık Gönül
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-5
Journal Detail:
Title:  Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis     Volume:  -     ISSN:  1744-2818     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433802     Medline TA:  Amyloid     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Endocrinology and Metabolism, Gazi University Faculty of Medicine , Ankara , Turkey.
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