Document Detail

Diffuse alveolar hemorrhage following administration of tirofiban or abciximab: a nemesis of platelet glycoprotein IIb/IIIa inhibitors.
MedLine Citation:
PMID:  10642769     Owner:  NLM     Status:  MEDLINE    
We describe three patients who developed severe pulmonary hemorrhage following administration of tirofiban (one patient) and abciximab (two patients). Pulmonary hemorrhage associated with abciximab use has been described, but to the best of our knowledge there has been no previous reports of this complication with tirofiban. Cathet. Cardiovasc. Intervent. 49:181-184, 2000.
A Ali; S Patil; K J Grady; T L Schreiber
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  49     ISSN:  1522-1946     ISO Abbreviation:  Catheter Cardiovasc Interv     Publication Date:  2000 Feb 
Date Detail:
Created Date:  2000-03-01     Completed Date:  2000-03-01     Revised Date:  2013-05-24    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  181-4     Citation Subset:  IM    
Copyright Information:
Copyright 2000 Wiley-Liss, Inc.
Department of Cardiology, St. John Hospital and Medical Center, Detroit, Michigan 48236, USA.
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MeSH Terms
Angioplasty, Balloon, Coronary
Antibodies, Monoclonal / adverse effects*
Fatal Outcome
Hemoptysis / chemically induced*
Immunoglobulin Fab Fragments / adverse effects*
Myocardial Ischemia / therapy
Platelet Aggregation Inhibitors / adverse effects*
Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors*
Pulmonary Alveoli
Thrombosis / prevention & control
Tyrosine / adverse effects,  analogs & derivatives*
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Immunoglobulin Fab Fragments; 0/Platelet Aggregation Inhibitors; 0/Platelet Glycoprotein GPIIb-IIIa Complex; 144494-65-5/tirofiban; 55520-40-6/Tyrosine; X85G7936GV/abciximab

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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