Document Detail


Differing haemodynamic stability due to differing sympathetic response: comparison of ultrafiltration, haemodialysis and haemofiltration.
MedLine Citation:
PMID:  7243770     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In 12 RDT patients the volume removal related haemodynamic changes were correlated with concomitant changes in sympathetic activity during pure ultrafiltration (UF), post dilution haemofiltration (HF) and haemodialysis using either acetate (HDA) or bicarbonate (HDB) as buffer substitute. Total peripheral resistance (TPR) and plasma noradrenaline concentrations (PNA) increased during UF indicating a qualitatively adequate reaction of ESRD patients to volume removal. This physiological response is maintained during HF, resulting in intratreatment haemodynamic stability. In contrast no increase of PNA and insignificant changes of TPR were seen in HDA and HDB. As small molecule clearances were matched to those in HF, the behaviour of PNA indicates that not PNA removal but an impaired sympathetic response during HDA and HDB is responsible for the inadequate rise of TPR.
Authors:
C A Baldamus; W Ernst; W Fassbinder; K M Koch
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association     Volume:  17     ISSN:  0071-2736     ISO Abbreviation:  Proc Eur Dial Transplant Assoc     Publication Date:  1980  
Date Detail:
Created Date:  1981-08-10     Completed Date:  1981-08-10     Revised Date:  2008-02-21    
Medline Journal Info:
Nlm Unique ID:  0355210     Medline TA:  Proc Eur Dial Transplant Assoc     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  205-12     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood*
Female
Hemodynamics*
Humans
Kidney Diseases / physiopathology,  therapy
Male
Middle Aged
Norepinephrine / blood
Renal Dialysis*
Sympathetic Nervous System / physiopathology*
Ultrafiltration*
Vascular Resistance
Grant Support
ID/Acronym/Agency:
N01-AM-8-227/AM/NIADDK NIH HHS
Chemical
Reg. No./Substance:
51-41-2/Norepinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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