Document Detail


Differentiation of mesenchymal multipotent stromal cells of the lungs in pneumofibrosis.
MedLine Citation:
PMID:  23486599     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
We studied differentiation of multipotent mesenchymal stromal cells (MMSC) of the lungs of C57Bl/6 mice with bleomycin-induced pneumofibrosis. Adherent mononuclear cells found in mouse lungs demonstrated mesenchymal phenotype and expressed CD44, CD73, CD90, and CD106, but not CD31, CD34, and CD45. The cells with MMSC characteristics differentiate in vitro into various cells of stromal lines (chondrocytes, osteogenic cells, adipocytes, and fibroblasts). Bleomycin increased the growth rate of MMSC and selectively promoted their differentiation towards fibroblast cells.
Authors:
E G Skurikhin; E S Khmelevskaya; O V Pershina; N N Ermakova; V A Krupin; A M Reztsova; L A Ermolaeva; V D Yakushina; I E Stepanova; V M Reztsova; N V Cherdyntseva; M N Stakheeva; A M Dygai
Related Documents :
23418439 - Silencing of ape1 enhances sensitivity of human hepatocellular carcinoma cells to radio...
24223799 - Alternative signaling pathways as potential therapeutic targets for overcoming egfr and...
24120669 - Osteoblastic cell secretome: a novel role for progranulin during risedronate treatment.
24784579 - Cellular contractility and extracellular matrix stiffness regulate matrix metalloprotei...
24856959 - Force-controlled manipulation of single cells: from afm to fluidfm.
23913259 - Visualizing snvs to quantify allele-specific expression in single cells.
20376489 - Sulfated polysaccharides from marine sponges: conspicuous distribution among different ...
7927309 - Nodular foci in parathyroid adenomas and hyperplasias: an immunohistochemical analysis ...
22893409 - Determination of beta-cell function: ion channel function in beta cells.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bulletin of experimental biology and medicine     Volume:  154     ISSN:  1573-8221     ISO Abbreviation:  Bull. Exp. Biol. Med.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-03-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372557     Medline TA:  Bull Exp Biol Med     Country:  United States    
Other Details:
Languages:  eng; rus     Pagination:  537-43     Citation Subset:  IM    
Affiliation:
Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia. ovpershina@gmail.com.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Comparative Analysis of the Expression of Neural Stem Cell-Associated Genes during Neocortex and Ret...
Next Document:  Usage of Plasmid Vector Carrying vegf and fgf2 Genes after Spinal Cord Injury in Rats.