| Differentiation between recurrent tumor and benign conditions after treatment of gynecologic pelvic carcinoma: value of dynamic contrast-enhanced subtraction MR imaging. | |
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MedLine Citation:
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PMID: 9205223 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To compare dynamic contrast material-enhanced subtraction and T2-weighted spin-echo (SE) magnetic resonance (MR) imaging in the differentiation of fibrosis from tumor recurrence during the follow-up of treated gynecologic pelvic malignancy. MATERIALS AND METHODS: Thirty-four patients (aged 24-82 years) with 18 benign and 35 malignant lesions confirmed by means of surgery (n = 18), biopsy (n = 25), or 18-month follow-up examination (n = 10) underwent dynamic contrast-enhanced subtraction and T2-weighted SE MR imaging. Contrast material enhancement of an abnormal pelvic structure within the first 90 seconds on dynamic contrast-enhanced subtraction images or high signal intensity on T2-weighted SE images was considered indicative of malignancy. RESULTS: The sensitivity, specificity, accuracy, and positive and negative predictive values were 91%, 67%, 83%, 86%, and 86%, respectively, for dynamic contrast-enhanced subtraction imaging and 91%, 22%, 68%, 70%, and 57%, respectively, for T2-weighted SE imaging. More lesions were correctly classified with dynamic contrast-enhanced subtraction imaging than with T2-weighted SE imaging (P < .01). CONCLUSION: Dynamic contrast-enhanced subtraction imaging is more accurate than T2-weighted SE imaging for differentiating fibrosis from tumor recurrence during the follow-up of treated gynecologic pelvic malignancy. However, use of both sequences is recommended. |
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Authors:
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K Kinkel; M Ariche; A A Tardivon; A Spatz; D Castaigne; C Lhomme; D Vanel |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Radiology Volume: 204 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 1997 Jul |
Date Detail:
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Created Date: 1997-07-17 Completed Date: 1997-07-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 55-63 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, Institut Gustave Roussy, Villejuif, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aftercare Aged Aged, 80 and over Biopsy Diagnosis, Differential Female Fibrosis Genital Diseases, Female / pathology* Genital Neoplasms, Female / pathology*, surgery Humans Inflammation Magnetic Resonance Imaging / standards* Middle Aged Neoplasm Recurrence, Local / pathology*, surgery Prospective Studies Radiotherapy, Adjuvant Reproducibility of Results Sensitivity and Specificity Subtraction Technique / standards* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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