| Differentiation of Stem Cells into Insulin-Producing Cells: Current Status and Challenges. | |
| | |
MedLine Citation:
|
PMID: 23283518 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Diabetes mellitus is one of the most serious public health challenges of the twenty-first century. Allogenic islet transplantation is an efficient therapy for type 1 diabetes. However, immune rejection, side effects of immunosuppressive treatment as well as lack of sufficient donor organs limits its potential. In recent years, several promising approaches for generation of new pancreatic β cells have been developed. This review provides an overview of current status of pancreatic and extra-pancreatic stem cells differentiation into insulin-producing cells and the possible application of these cells for diabetes treatment. The PubMed database was searched for English language articles published between 2001 and 2012, using the keyword combinations: diabetes mellitus, differentiation, insulin-producing cells, stem cells. |
| | |
Authors:
|
Marta Pokrywczynska; Sandra Krzyzanowska; Arkadiusz Jundzill; Jan Adamowicz; Tomasz Drewa |
Related Documents
:
|
23531958 - Glucocorticoid-induced hyperglycemia. 23021818 - Diabetes foot disease: the cinderella of australian diabetes management? 23489968 - Novel therapies for management of type 2 diabetes mellitus part 2 - addressing the incr... 23140648 - Beyond white blood cell monitoring: screening in the initial phase of clozapine therapy. 3081568 - Impaired hypoxic ventilatory drive in diabetic patients with autonomic neuropathy. 11732808 - Streptozocin-induced pancreatic islet destruction in beef cows. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2013-1-3 |
Journal Detail:
|
Title: Archivum immunologiae et therapiae experimentalis Volume: - ISSN: 1661-4917 ISO Abbreviation: Arch. Immunol. Ther. Exp. (Warsz.) Publication Date: 2013 Jan |
Date Detail:
|
Created Date: 2013-1-3 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0114365 Medline TA: Arch Immunol Ther Exp (Warsz) Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Tissue Engineering, Ludwik Rydygier Medical College in Bydgoszcz, Nicolaus Copernicus University in Torun, Karlowicza 24, 85-092, Bydgoszcz, Poland, marta.pokrywczynska@interia.pl. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Brain-Derived Neurotrophic Factor in Neuroimmunology: Lessons Learned from Multiple Sclerosis Patien...
Next Document: Pretreatment Levels of Vascular Endothelial Growth Factor in Plasma Predict a Complete Remission Rat...