Document Detail


Differentiation of Stem Cells into Insulin-Producing Cells: Current Status and Challenges.
MedLine Citation:
PMID:  23283518     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Diabetes mellitus is one of the most serious public health challenges of the twenty-first century. Allogenic islet transplantation is an efficient therapy for type 1 diabetes. However, immune rejection, side effects of immunosuppressive treatment as well as lack of sufficient donor organs limits its potential. In recent years, several promising approaches for generation of new pancreatic β cells have been developed. This review provides an overview of current status of pancreatic and extra-pancreatic stem cells differentiation into insulin-producing cells and the possible application of these cells for diabetes treatment. The PubMed database was searched for English language articles published between 2001 and 2012, using the keyword combinations: diabetes mellitus, differentiation, insulin-producing cells, stem cells.
Authors:
Marta Pokrywczynska; Sandra Krzyzanowska; Arkadiusz Jundzill; Jan Adamowicz; Tomasz Drewa
Related Documents :
23148758 - Dendritic cell therapy for type 1 diabetes suppression.
23356568 - Effects of pioglitazone and vildagliptin on coagulation cascade in diabetes mellitus - ...
23266468 - Non-alcoholic fatty liver disease and insulin resistance: from bench to bedside.
23398978 - Group follow-up compared to individual clinic visits after structured education for typ...
16639388 - Altered glucose metabolism in obese youth.
22584788 - Cellular and molecular mechanisms of diabetic glomerulopathy.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-3
Journal Detail:
Title:  Archivum immunologiae et therapiae experimentalis     Volume:  -     ISSN:  1661-4917     ISO Abbreviation:  Arch. Immunol. Ther. Exp. (Warsz.)     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0114365     Medline TA:  Arch Immunol Ther Exp (Warsz)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Tissue Engineering, Ludwik Rydygier Medical College in Bydgoszcz, Nicolaus Copernicus University in Torun, Karlowicza 24, 85-092, Bydgoszcz, Poland, marta.pokrywczynska@interia.pl.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Brain-Derived Neurotrophic Factor in Neuroimmunology: Lessons Learned from Multiple Sclerosis Patien...
Next Document:  Pretreatment Levels of Vascular Endothelial Growth Factor in Plasma Predict a Complete Remission Rat...