| Differentiation of Parkinson's disease and atypical parkinsonian syndromes by transcranial ultrasound. | |
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MedLine Citation:
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PMID: 15716540 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Neuroimaging is known to complement clinical findings in the diagnostic work up of parkinsonian syndromes. Recently, transcranial ultrasound was reported to have a high diagnostic yield in differentiating idiopathic Parkinson's disease (IPD) from atypical parkinsonian syndromes. This report summarises the sonographic findings of 102 patients with IPD, 34 patients with multiple system atrophy, and 21 patients with progressive supranuclear palsy. Increased echogenicity of the substantia nigra is predictive for IPD whereas a low echogenic substantia nigra, particularly when combined with a hyperechogenic lentiform nucleus, strongly suggests an atypical Parkinsonian syndrome. The underlying causes for the differential echo pattern of the substantia nigra remain unknown. |
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Authors:
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S Behnke; D Berg; M Naumann; G Becker |
Publication Detail:
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Type: Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of neurology, neurosurgery, and psychiatry Volume: 76 ISSN: 0022-3050 ISO Abbreviation: J. Neurol. Neurosurg. Psychiatr. Publication Date: 2005 Mar |
Date Detail:
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Created Date: 2005-02-17 Completed Date: 2005-03-15 Revised Date: 2008-11-20 |
Medline Journal Info:
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Nlm Unique ID: 2985191R Medline TA: J Neurol Neurosurg Psychiatry Country: England |
Other Details:
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Languages: eng Pagination: 423-5 Citation Subset: IM |
Affiliation:
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Department of Neurology, University of the Saarland, Gebäude 9066421 Homburg/Saar, Germany. nesbeh@uniklinik-saarland.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Diagnosis, Differential Female Humans Male Middle Aged Multiple System Atrophy / ultrasonography Observer Variation Parkinson Disease / ultrasonography* Parkinsonian Disorders / ultrasonography* Sensitivity and Specificity Skull / ultrasonography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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