| Differentiation of intraductal growing-type cholangiocarcinomas from nodular-type cholangiocarcinomas at biliary MR imaging with MR cholangiography. | |
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MedLine Citation:
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PMID: 20829532 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To describe the magnetic resonance (MR) findings of intraductal growing (IDG)-type cholangiocarcinoma (CC) and to identify the features that differentiate it from nodular-type CC. MATERIALS AND METHODS: The institutional review board approved this retrospective study and waived the informed consent requirement. Thirty-nine patients with pathologically proved IDG-type (n = 19) or nodular-type (n = 20) CCs who had undergone preoperative gadolinium-enhanced MR imaging with MR cholangiography were included in this study. Analysis of MR findings included determination of the (a) shape, enhancement degree, and pattern of the tumor; (b) outer caliber of the tumor-bearing segment; and (c) presence of tumor multiplicity, upstream and downstream bile duct dilatation, bile duct wall thickening adjacent to the tumor, and adjacent organ invasion. The significance of these findings was determined with the χ² test. RESULTS: Significant features in the differentiation of IDG-type CCs from nodular-type CCs included papillary or irregular polypoid shape, lack of constriction of the tumor-bearing segment, hypoenhancement of the tumor to the liver during the equilibrium phase, tumor multiplicity, upstream and downstream bile duct dilatation, and no bile duct wall thickening adjacent to the tumor (P < .05). When at least two of these six imaging features were used in combination, sensitivity and specificity in the diagnosis of IDG-type CCs were 95% and 70%, respectively. CONCLUSION: By using characteristic MR features, one can differentiate IDG-type CC from nodular-type CC with a high degree of accuracy at biliary MR imaging with MR cholangiography. |
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Authors:
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Ji Eun Kim; Jeong Min Lee; Seung Ho Kim; Jee Hyun Baek; Sung Kyung Moon; In Sun Yu; Se Hyung Kim; Jae Young Lee; Joon Koo Han; Byung Ihn Choi |
Publication Detail:
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Type: Journal Article Date: 2010-09-09 |
Journal Detail:
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Title: Radiology Volume: 257 ISSN: 1527-1315 ISO Abbreviation: Radiology Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-20 Completed Date: 2010-12-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: United States |
Other Details:
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Languages: eng Pagination: 364-72 Citation Subset: AIM; IM |
Copyright Information:
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© RSNA, 2010. |
Affiliation:
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Department of Radiology, Seoul National University Hospital, 28 Yeongon-dong, Jongno-gu, Seoul 110-744, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Bile Duct Neoplasms / pathology* Bile Ducts, Intrahepatic / pathology* Chi-Square Distribution Cholangiocarcinoma / pathology* Cholangiopancreatography, Magnetic Resonance / methods* Contrast Media / diagnostic use Diagnosis, Differential Female Humans Image Interpretation, Computer-Assisted Imaging, Three-Dimensional Male Meglumine / analogs & derivatives, diagnostic use Middle Aged Organometallic Compounds / diagnostic use Retrospective Studies Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Organometallic Compounds; 113662-23-0/gadobenic acid; 6284-40-8/Meglumine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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