Document Detail


Differentiating osteoradionecrosis from nasopharyngeal carcinoma tumour recurrence using 99Tcm-sestamibi SPECT/CT.
MedLine Citation:
PMID:  21849357     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Osteoradionecrosis (ORN) of the base of skull is a known complication of external beam radiotherapy in the treatment of nasopharyngeal carcinoma, and is widely believed to be sequelae of radiation-induced endarteritis, leading to cellular death and fibrosis. Differentiating ORN from tumour recurrence is challenging and has direct clinical implications. We present a case where (99)Tc(m)-sestamibi SPECT/CT was used to differentiate ORN from tumour recurrence and in which prior imaging using bone scintigraphy and fluorodeoxyglucose PET/CT were equivocal.
Authors:
A E H Tan; D C E Ng
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of radiology     Volume:  84     ISSN:  1748-880X     ISO Abbreviation:  Br J Radiol     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-08-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0373125     Medline TA:  Br J Radiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  e172-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Nuclear Medicine and PET, Singapore General Hospital, Singapore.
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