Document Detail

Differentiating autistic children with quantitative encephalography: a 3-month longitudinal study.
MedLine Citation:
PMID:  16901444     Owner:  NLM     Status:  MEDLINE    
The present study used a single-channel quantitative electroencephalographic (EEG) assessment to differentiate autistic children from normal control subjects. One hundred five normal and 17 autistic children participated in the study. In addition to amplitude measures of the frequency bands of delta, theta, alpha, sensorimotor rhythm, and beta and the theta to beta ratio, intra- (6 minutes) and intersessional (3 months) consistencies were also examined. The results indicated that autistic children showed significantly higher quantitative EEG amplitudes in many of the frequency bands than normal children; furthermore, their quantitative EEG activities were found to be relatively unstable within a 6-minute session compared with normal children. Discriminant function analyses revealed that absolute sensorimotor rhythm and beta amplitudes were the best predictors that correctly differentiated autistic children from normal children in the present sample, with a high accuracy rate of 95.2%. In addition, quantitative EEG measurements of normal and autistic children were found to be generally consistent across the 3-month period.
Agnes S Chan; Winnie W M Leung
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of child neurology     Volume:  21     ISSN:  0883-0738     ISO Abbreviation:  J. Child Neurol.     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-08-11     Completed Date:  2006-10-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  391-9     Citation Subset:  IM    
Neurology Laboratory, Department of of Psychology, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, China.
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MeSH Terms
Autistic Disorder / physiopathology*,  psychology
Brain / physiopathology*
Case-Control Studies
Longitudinal Studies
Multivariate Analysis
Reproducibility of Results

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