Document Detail

Differential silver carbonate staining of sister chromatids in BrdU-substituted chromsomes.
MedLine Citation:
PMID:  75163     Owner:  NLM     Status:  MEDLINE    
Differential staining of sister chromatids in BrdU-substituted human chromosomes is demonstrated by an ammoniacal silver carbonate procedure. With this method the chromosomes exhibit a subchromatid structure. Because proteolytic treatment indicated that the silver carbonate binds the chromosome proteins, changes of these components may be inferred in the BrdU-substituted chromosomes. Sister chromatid exchanges could be identified.
V J Goyanes
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Human genetics     Volume:  40     ISSN:  0340-6717     ISO Abbreviation:  Hum. Genet.     Publication Date:  1978 Jan 
Date Detail:
Created Date:  1978-04-17     Completed Date:  1978-04-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7613873     Medline TA:  Hum Genet     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  205-8     Citation Subset:  IM    
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MeSH Terms
Chromosomes, Human
Protein Binding
Staining and Labeling*
Reg. No./Substance:
59-14-3/Bromodeoxyuridine; 7440-22-4/Silver

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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