Document Detail

Differential response to pain by very premature neonates.
MedLine Citation:
PMID:  7478691     Owner:  NLM     Status:  MEDLINE    
The ability of very low birth weight (VLBW) premature infants to respond differentially to real versus a sham heelstick conditions was examined in this crossover study. Using a multidimensional assessment of responses of premature infants (n = 48) between 26 and 31 weeks gestational age (GA) at the time of the study, it was found that they respond differentially to real versus sham heelstick both behaviourally and physiologically. The multivariate effect of condition (real/sham) was significant with maximum heart rate and upper facial action (lower facial action was not scored) contributing significantly to the main effect. GA had a main multivariate effect, with the younger infants responding less robustly. The variability outcome measures of heart rate standard deviation and range of transfontanelle intracranial pressure contributed significantly to the main effect of GA, but not to the effect of condition. Young VLBW premature infants are capable of a multidimensional differential response to pain. GA is an important factor to consider when assessing pain in premature infants.
C C Johnston; B J Stevens; F Yang; L Horton
Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pain     Volume:  61     ISSN:  0304-3959     ISO Abbreviation:  Pain     Publication Date:  1995 Jun 
Date Detail:
Created Date:  1995-11-24     Completed Date:  1995-11-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7508686     Medline TA:  Pain     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  471-9     Citation Subset:  IM    
McGill University School of Nursing, Montreal, Canada.
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MeSH Terms
Cross-Over Studies
Discrimination Learning / physiology*
Infant, Newborn
Infant, Premature, Diseases / physiopathology,  psychology*
Infant, Very Low Birth Weight / physiology,  psychology*
Multivariate Analysis
Pain / physiopathology*

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